A retrospective analysis of the clinical efficacies of Q-switched Alexandrite and Q-switched Nd

YAG lasers in the treatment of nevus of Ota in Korean patients

Jae Eun Choi, Joo Bong Lee, Ki Beom Park, Bang Soon Kim, Un Cheol Yeo, Chang Hun Huh, Jie Hoon Kim, Young Chul Kye

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: While the Q-switched Alexandrite laser (QSAL) and the Q-switched neodymium: yttrium-aluminum-garnet (QSNY) laser have been widely used in treating nevus of Ota, few studies compared them. Objective: To compare the efficacies of the QSAL and the QSNY laser in the treatment of nevus of Ota in Korean patients. Methods and materials: A retrospective multicenter study was conducted in 76 patients with nevus of Ota. Thirty-one patients were treated with a QSAL (5.5-8.0-J/cm2, 4-mm spot size) and 45 patients were treated with QSNY laser (6.0-12.0-J/cm2, 2-mm spot size). Treatment outcomes were categorized into five grades and the results were compared with the relevant variables taken into account using multivariate logistic regression analysis. Results: QSAL treatment was more likely to achieve a better response compared with that with QSNY laser treatment. The odds ratio of achieving an excellent response, compared with the odds ratio of having a poor response, was 12.213-times more likely when a QSAL was used than when a QSNY laser was used (p-=-0.026). Conclusion: The QSAL tends to be more efficient than the QSNY laser in the treatment of nevus of Ota in Korean patients. Further controlled, prospective comparison studies are needed.

Original languageEnglish
Pages (from-to)240-245
Number of pages6
JournalJournal of Dermatological Treatment
Volume26
Issue number3
DOIs
Publication statusPublished - 2015 Jan 1

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Nevus of Ota
Solid-State Lasers
Neodymium
Lasers
Therapeutics
alexandrite
Odds Ratio

Keywords

  • Nevus of Ota
  • Q-switched 1064-nm neodymium: yttrium-aluminum-garnet laser
  • Q-switched 755-nm Alexandrite laser

ASJC Scopus subject areas

  • Dermatology

Cite this

A retrospective analysis of the clinical efficacies of Q-switched Alexandrite and Q-switched Nd : YAG lasers in the treatment of nevus of Ota in Korean patients. / Choi, Jae Eun; Lee, Joo Bong; Park, Ki Beom; Kim, Bang Soon; Yeo, Un Cheol; Huh, Chang Hun; Kim, Jie Hoon; Kye, Young Chul.

In: Journal of Dermatological Treatment, Vol. 26, No. 3, 01.01.2015, p. 240-245.

Research output: Contribution to journalArticle

Choi, Jae Eun ; Lee, Joo Bong ; Park, Ki Beom ; Kim, Bang Soon ; Yeo, Un Cheol ; Huh, Chang Hun ; Kim, Jie Hoon ; Kye, Young Chul. / A retrospective analysis of the clinical efficacies of Q-switched Alexandrite and Q-switched Nd : YAG lasers in the treatment of nevus of Ota in Korean patients. In: Journal of Dermatological Treatment. 2015 ; Vol. 26, No. 3. pp. 240-245.
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abstract = "Background: While the Q-switched Alexandrite laser (QSAL) and the Q-switched neodymium: yttrium-aluminum-garnet (QSNY) laser have been widely used in treating nevus of Ota, few studies compared them. Objective: To compare the efficacies of the QSAL and the QSNY laser in the treatment of nevus of Ota in Korean patients. Methods and materials: A retrospective multicenter study was conducted in 76 patients with nevus of Ota. Thirty-one patients were treated with a QSAL (5.5-8.0-J/cm2, 4-mm spot size) and 45 patients were treated with QSNY laser (6.0-12.0-J/cm2, 2-mm spot size). Treatment outcomes were categorized into five grades and the results were compared with the relevant variables taken into account using multivariate logistic regression analysis. Results: QSAL treatment was more likely to achieve a better response compared with that with QSNY laser treatment. The odds ratio of achieving an excellent response, compared with the odds ratio of having a poor response, was 12.213-times more likely when a QSAL was used than when a QSNY laser was used (p-=-0.026). Conclusion: The QSAL tends to be more efficient than the QSNY laser in the treatment of nevus of Ota in Korean patients. Further controlled, prospective comparison studies are needed.",
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T2 - YAG lasers in the treatment of nevus of Ota in Korean patients

AU - Choi, Jae Eun

AU - Lee, Joo Bong

AU - Park, Ki Beom

AU - Kim, Bang Soon

AU - Yeo, Un Cheol

AU - Huh, Chang Hun

AU - Kim, Jie Hoon

AU - Kye, Young Chul

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Background: While the Q-switched Alexandrite laser (QSAL) and the Q-switched neodymium: yttrium-aluminum-garnet (QSNY) laser have been widely used in treating nevus of Ota, few studies compared them. Objective: To compare the efficacies of the QSAL and the QSNY laser in the treatment of nevus of Ota in Korean patients. Methods and materials: A retrospective multicenter study was conducted in 76 patients with nevus of Ota. Thirty-one patients were treated with a QSAL (5.5-8.0-J/cm2, 4-mm spot size) and 45 patients were treated with QSNY laser (6.0-12.0-J/cm2, 2-mm spot size). Treatment outcomes were categorized into five grades and the results were compared with the relevant variables taken into account using multivariate logistic regression analysis. Results: QSAL treatment was more likely to achieve a better response compared with that with QSNY laser treatment. The odds ratio of achieving an excellent response, compared with the odds ratio of having a poor response, was 12.213-times more likely when a QSAL was used than when a QSNY laser was used (p-=-0.026). Conclusion: The QSAL tends to be more efficient than the QSNY laser in the treatment of nevus of Ota in Korean patients. Further controlled, prospective comparison studies are needed.

AB - Background: While the Q-switched Alexandrite laser (QSAL) and the Q-switched neodymium: yttrium-aluminum-garnet (QSNY) laser have been widely used in treating nevus of Ota, few studies compared them. Objective: To compare the efficacies of the QSAL and the QSNY laser in the treatment of nevus of Ota in Korean patients. Methods and materials: A retrospective multicenter study was conducted in 76 patients with nevus of Ota. Thirty-one patients were treated with a QSAL (5.5-8.0-J/cm2, 4-mm spot size) and 45 patients were treated with QSNY laser (6.0-12.0-J/cm2, 2-mm spot size). Treatment outcomes were categorized into five grades and the results were compared with the relevant variables taken into account using multivariate logistic regression analysis. Results: QSAL treatment was more likely to achieve a better response compared with that with QSNY laser treatment. The odds ratio of achieving an excellent response, compared with the odds ratio of having a poor response, was 12.213-times more likely when a QSAL was used than when a QSNY laser was used (p-=-0.026). Conclusion: The QSAL tends to be more efficient than the QSNY laser in the treatment of nevus of Ota in Korean patients. Further controlled, prospective comparison studies are needed.

KW - Nevus of Ota

KW - Q-switched 1064-nm neodymium: yttrium-aluminum-garnet laser

KW - Q-switched 755-nm Alexandrite laser

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