A rhodamine based fluorescent probe validates substrate and cellular hypoxia specific NADH expression

Arup Podder, Seyoung Koo, Jiyeong Lee, Sora Mun, Sabina Khatun, Hee Gyoo Kang, Sankarprasad Bhuniya, Jong Seung Kim

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Herein, we report a rhodamine-based redox probe (MQR) to visualize cytosolic NADH in the cellular milieu. Its high sensitivity and selectivity allowed it to track the alteration of the NADH level under metabolic perturbation, suggesting its potential as a useful tool to study the association between the NADH level and metabolic abnormalities with clinical significance.

Original languageEnglish
Pages (from-to)537-540
Number of pages4
JournalChemical Communications
Volume55
Issue number4
DOIs
Publication statusPublished - 2019 Jan 1

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Cell Hypoxia
Rhodamines
Fluorescent Dyes
NAD
Substrates
Oxidation-Reduction

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

A rhodamine based fluorescent probe validates substrate and cellular hypoxia specific NADH expression. / Podder, Arup; Koo, Seyoung; Lee, Jiyeong; Mun, Sora; Khatun, Sabina; Kang, Hee Gyoo; Bhuniya, Sankarprasad; Kim, Jong Seung.

In: Chemical Communications, Vol. 55, No. 4, 01.01.2019, p. 537-540.

Research output: Contribution to journalArticle

Podder, Arup ; Koo, Seyoung ; Lee, Jiyeong ; Mun, Sora ; Khatun, Sabina ; Kang, Hee Gyoo ; Bhuniya, Sankarprasad ; Kim, Jong Seung. / A rhodamine based fluorescent probe validates substrate and cellular hypoxia specific NADH expression. In: Chemical Communications. 2019 ; Vol. 55, No. 4. pp. 537-540.
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