A schiff base fluorescence enhancement probe for Fe(III) and its sensing applications in cancer cells

Na Hee Kim, Junho Lee, Sungnam Park, Junyang Jung, Dokyoung Kim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We report a new Schiff base fluorescent probe which senses ferric ion, Fe(III), with a significant fluorescence enhancement response. The probe showed high sensitivity (0.8 ppb), and fast response time (<10 s) of Fe(III) in aqueous media. In addition, the probe showed the ability to sense Fe(III) in a HeLa cancer cell line, with very low cytotoxicity. As a new bio-imaging probe for Fe(III), it gave bright fluorescent images in confocal laser scanning microscopy (CLSM).

Original languageEnglish
Article number2500
JournalSensors (Switzerland)
Volume19
Issue number11
DOIs
Publication statusPublished - 2019 Jun 1

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Keywords

  • Bioimaging
  • D-A type fluorophore
  • Fluorescent probe
  • Iron ion sensing
  • Schiff base probe

ASJC Scopus subject areas

  • Analytical Chemistry
  • Atomic and Molecular Physics, and Optics
  • Biochemistry
  • Instrumentation
  • Electrical and Electronic Engineering

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