A schiff base fluorescence enhancement probe for Fe(III) and its sensing applications in cancer cells

Na Hee Kim, Junho Lee, Sungnam Park, Junyang Jung, Dokyoung Kim

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We report a new Schiff base fluorescent probe which senses ferric ion, Fe(III), with a significant fluorescence enhancement response. The probe showed high sensitivity (0.8 ppb), and fast response time (<10 s) of Fe(III) in aqueous media. In addition, the probe showed the ability to sense Fe(III) in a HeLa cancer cell line, with very low cytotoxicity. As a new bio-imaging probe for Fe(III), it gave bright fluorescent images in confocal laser scanning microscopy (CLSM).

Original languageEnglish
Article number2500
JournalSensors (Switzerland)
Volume19
Issue number11
DOIs
Publication statusPublished - 2019 Jun 1

Fingerprint

Aptitude
Schiff Bases
Fluorescent Dyes
HeLa Cells
Confocal Microscopy
imines
Reaction Time
Fluorescence
cancer
Cells
Ions
Cell Line
fluorescence
augmentation
probes
Neoplasms
Cytotoxicity
ferric ions
Microscopic examination
cultured cells

Keywords

  • Bioimaging
  • D-A type fluorophore
  • Fluorescent probe
  • Iron ion sensing
  • Schiff base probe

ASJC Scopus subject areas

  • Analytical Chemistry
  • Atomic and Molecular Physics, and Optics
  • Biochemistry
  • Instrumentation
  • Electrical and Electronic Engineering

Cite this

A schiff base fluorescence enhancement probe for Fe(III) and its sensing applications in cancer cells. / Kim, Na Hee; Lee, Junho; Park, Sungnam; Jung, Junyang; Kim, Dokyoung.

In: Sensors (Switzerland), Vol. 19, No. 11, 2500, 01.06.2019.

Research output: Contribution to journalArticle

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