A stereocontrolled synthesis of methyl (-)-nonactate

Joon Won Jeong, Byoung Young Woo, Deok Chan Ha, Zaesung No

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

A stereoselective synthesis of methyl (-)-nonactate is described. (E)-γ-Triethylsilyloxyalkene 13 generated from sulfone 10 and (S)-2-benzyloxypropanal underwent intramolecular iodoetherification in the presence of silver carbonate to provide cis-2,5-disubstituted tetrahydrofuran 8 as a key intermediate.

Original languageEnglish
Pages (from-to)393-395
Number of pages3
JournalSynlett
Issue number3
Publication statusPublished - 2003

Keywords

  • Asymmetric synthesis
  • Cyclizations
  • Iodoetherifications
  • Nonactic acid
  • Sulfones

ASJC Scopus subject areas

  • Organic Chemistry

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