A study on the qualitative morphological features of the muscle and subcutaneous shapes in vivo using Fourier-domain common path OCT

Jae Ho Han, Liu Xuan, Jin U. Kang, Chul Gyu Song

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, we have demonstrated a polarization sensitive subcutaneous and muscle imaging based on common path optical coherence tomography (CP-OCT) using near infrared source. The axial and lateral resolutions of our PS-OCT system are 9μm and 6μm, respectively. The internal structural information has been extracted by the real-time signal analysis (Fourier Transform) from the modulated spectral intensity depending on the beam and tissue birefringence. Preliminary results using fresh beef and in vivo rat show that we can visualize the birefringence effect of the tissue collagen fibers in the samples for better image contrast and sensitivity for detection of hidden dermal structures. Compared to conventional CP-OCT, our proposed PS-OCT could provide depth-resolved images, which reflect tissue birefringence.

Original languageEnglish
Title of host publicationOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV
DOIs
Publication statusPublished - 2010
Externally publishedYes
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV - San Francisco, CA, United States
Duration: 2010 Jan 252010 Jan 27

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7554
ISSN (Print)1605-7422

Other

OtherOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV
CountryUnited States
CitySan Francisco, CA
Period10/1/2510/1/27

Keywords

  • Birefringence
  • Imaging
  • Infrared
  • Subcutaneous
  • Tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Han, J. H., Xuan, L., Kang, J. U., & Song, C. G. (2010). A study on the qualitative morphological features of the muscle and subcutaneous shapes in vivo using Fourier-domain common path OCT. In Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV [75542H] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7554). https://doi.org/10.1117/12.841923