A thin film polyimide mesh microelectrode for chronic epidural electrocorticography recording with enhanced contactability

Dong Hyun Baek, Jeyeon Lee, Hang Jin Byeon, Hoseok Choi, In Young Kim, Kyoung Min Lee, James Jungho Pak, Dong Pyo Jang, Sang Hoon Lee

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objective. Epidural electrocorticography (ECoG) activity may be more reliable and stable than single-unit-activity or local field potential. Invasive brain computer interface (BCI) devices are limited by mechanical mismatching and cellular reactive responses due to differences in the elastic modulus and the motion of stiff electrodes. We propose a mesh-shaped electrode to enhance the contactability between surface of dura and electrode. Approach. We designed a polyimide (PI) electrode with a mesh pattern for more conformal contact with a curved surface. We compared the contact capability of mesh PI electrodes with conventionally used sheet PI electrode. The electrical properties of the mesh PI electrode were evaluated for four weeks. We recorded the epidural ECoG (eECoG) activity on the surface of rhesus monkey brains while they performed a saccadic task for four months. Main results. The mesh PI electrode showed good contact with the agarose brain surface, as evaluated by visual inspection and signal measurement. It was about 87% accurate in predicting the direction of saccade eye movement. Significance. Our results indicate that the mesh PI electrode was flexible and good contact on the curved surface and can record eECoG activity maintaining close contact to dura, which was proved by in vivo and in vitro test.

Original languageEnglish
Article number046023
JournalJournal of Neural Engineering
Volume11
Issue number4
DOIs
Publication statusPublished - 2014 Aug 1

Fingerprint

Microelectrodes
Polyimides
Electrodes
Thin films
Eye movements
Brain
Brain-Computer Interfaces
Electrocorticography
Brain computer interface
Saccades
Elastic Modulus
Eye Movements
Macaca mulatta
Sepharose
Electric properties
Elastic moduli
Inspection
Equipment and Supplies

ASJC Scopus subject areas

  • Biomedical Engineering
  • Cellular and Molecular Neuroscience

Cite this

A thin film polyimide mesh microelectrode for chronic epidural electrocorticography recording with enhanced contactability. / Baek, Dong Hyun; Lee, Jeyeon; Byeon, Hang Jin; Choi, Hoseok; Kim, In Young; Lee, Kyoung Min; Pak, James Jungho; Jang, Dong Pyo; Lee, Sang Hoon.

In: Journal of Neural Engineering, Vol. 11, No. 4, 046023, 01.08.2014.

Research output: Contribution to journalArticle

Baek, Dong Hyun ; Lee, Jeyeon ; Byeon, Hang Jin ; Choi, Hoseok ; Kim, In Young ; Lee, Kyoung Min ; Pak, James Jungho ; Jang, Dong Pyo ; Lee, Sang Hoon. / A thin film polyimide mesh microelectrode for chronic epidural electrocorticography recording with enhanced contactability. In: Journal of Neural Engineering. 2014 ; Vol. 11, No. 4.
@article{310e6bb5170949cb990b7ffab6c14f11,
title = "A thin film polyimide mesh microelectrode for chronic epidural electrocorticography recording with enhanced contactability",
abstract = "Objective. Epidural electrocorticography (ECoG) activity may be more reliable and stable than single-unit-activity or local field potential. Invasive brain computer interface (BCI) devices are limited by mechanical mismatching and cellular reactive responses due to differences in the elastic modulus and the motion of stiff electrodes. We propose a mesh-shaped electrode to enhance the contactability between surface of dura and electrode. Approach. We designed a polyimide (PI) electrode with a mesh pattern for more conformal contact with a curved surface. We compared the contact capability of mesh PI electrodes with conventionally used sheet PI electrode. The electrical properties of the mesh PI electrode were evaluated for four weeks. We recorded the epidural ECoG (eECoG) activity on the surface of rhesus monkey brains while they performed a saccadic task for four months. Main results. The mesh PI electrode showed good contact with the agarose brain surface, as evaluated by visual inspection and signal measurement. It was about 87{\%} accurate in predicting the direction of saccade eye movement. Significance. Our results indicate that the mesh PI electrode was flexible and good contact on the curved surface and can record eECoG activity maintaining close contact to dura, which was proved by in vivo and in vitro test.",
keywords = "brain-computer interface, epidural ECoG, neural prosthetics",
author = "Baek, {Dong Hyun} and Jeyeon Lee and Byeon, {Hang Jin} and Hoseok Choi and Kim, {In Young} and Lee, {Kyoung Min} and Pak, {James Jungho} and Jang, {Dong Pyo} and Lee, {Sang Hoon}",
year = "2014",
month = "8",
day = "1",
doi = "10.1088/1741-2560/11/4/046023",
language = "English",
volume = "11",
journal = "Journal of Neural Engineering",
issn = "1741-2560",
publisher = "IOP Publishing Ltd.",
number = "4",

}

TY - JOUR

T1 - A thin film polyimide mesh microelectrode for chronic epidural electrocorticography recording with enhanced contactability

AU - Baek, Dong Hyun

AU - Lee, Jeyeon

AU - Byeon, Hang Jin

AU - Choi, Hoseok

AU - Kim, In Young

AU - Lee, Kyoung Min

AU - Pak, James Jungho

AU - Jang, Dong Pyo

AU - Lee, Sang Hoon

PY - 2014/8/1

Y1 - 2014/8/1

N2 - Objective. Epidural electrocorticography (ECoG) activity may be more reliable and stable than single-unit-activity or local field potential. Invasive brain computer interface (BCI) devices are limited by mechanical mismatching and cellular reactive responses due to differences in the elastic modulus and the motion of stiff electrodes. We propose a mesh-shaped electrode to enhance the contactability between surface of dura and electrode. Approach. We designed a polyimide (PI) electrode with a mesh pattern for more conformal contact with a curved surface. We compared the contact capability of mesh PI electrodes with conventionally used sheet PI electrode. The electrical properties of the mesh PI electrode were evaluated for four weeks. We recorded the epidural ECoG (eECoG) activity on the surface of rhesus monkey brains while they performed a saccadic task for four months. Main results. The mesh PI electrode showed good contact with the agarose brain surface, as evaluated by visual inspection and signal measurement. It was about 87% accurate in predicting the direction of saccade eye movement. Significance. Our results indicate that the mesh PI electrode was flexible and good contact on the curved surface and can record eECoG activity maintaining close contact to dura, which was proved by in vivo and in vitro test.

AB - Objective. Epidural electrocorticography (ECoG) activity may be more reliable and stable than single-unit-activity or local field potential. Invasive brain computer interface (BCI) devices are limited by mechanical mismatching and cellular reactive responses due to differences in the elastic modulus and the motion of stiff electrodes. We propose a mesh-shaped electrode to enhance the contactability between surface of dura and electrode. Approach. We designed a polyimide (PI) electrode with a mesh pattern for more conformal contact with a curved surface. We compared the contact capability of mesh PI electrodes with conventionally used sheet PI electrode. The electrical properties of the mesh PI electrode were evaluated for four weeks. We recorded the epidural ECoG (eECoG) activity on the surface of rhesus monkey brains while they performed a saccadic task for four months. Main results. The mesh PI electrode showed good contact with the agarose brain surface, as evaluated by visual inspection and signal measurement. It was about 87% accurate in predicting the direction of saccade eye movement. Significance. Our results indicate that the mesh PI electrode was flexible and good contact on the curved surface and can record eECoG activity maintaining close contact to dura, which was proved by in vivo and in vitro test.

KW - brain-computer interface

KW - epidural ECoG

KW - neural prosthetics

UR - http://www.scopus.com/inward/record.url?scp=84904652411&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84904652411&partnerID=8YFLogxK

U2 - 10.1088/1741-2560/11/4/046023

DO - 10.1088/1741-2560/11/4/046023

M3 - Article

C2 - 25024292

AN - SCOPUS:84904652411

VL - 11

JO - Journal of Neural Engineering

JF - Journal of Neural Engineering

SN - 1741-2560

IS - 4

M1 - 046023

ER -