A thin film polyimide mesh microelectrode for chronic epidural electrocorticography recording with enhanced contactability

Dong Hyun Baek, Jeyeon Lee, Hang Jin Byeon, Hoseok Choi, In Young Kim, Kyoung Min Lee, James Jungho Pak, Dong Pyo Jang, Sang Hoon Lee

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objective. Epidural electrocorticography (ECoG) activity may be more reliable and stable than single-unit-activity or local field potential. Invasive brain computer interface (BCI) devices are limited by mechanical mismatching and cellular reactive responses due to differences in the elastic modulus and the motion of stiff electrodes. We propose a mesh-shaped electrode to enhance the contactability between surface of dura and electrode. Approach. We designed a polyimide (PI) electrode with a mesh pattern for more conformal contact with a curved surface. We compared the contact capability of mesh PI electrodes with conventionally used sheet PI electrode. The electrical properties of the mesh PI electrode were evaluated for four weeks. We recorded the epidural ECoG (eECoG) activity on the surface of rhesus monkey brains while they performed a saccadic task for four months. Main results. The mesh PI electrode showed good contact with the agarose brain surface, as evaluated by visual inspection and signal measurement. It was about 87% accurate in predicting the direction of saccade eye movement. Significance. Our results indicate that the mesh PI electrode was flexible and good contact on the curved surface and can record eECoG activity maintaining close contact to dura, which was proved by in vivo and in vitro test.

Original languageEnglish
Article number046023
JournalJournal of Neural Engineering
Volume11
Issue number4
DOIs
Publication statusPublished - 2014 Aug 1

ASJC Scopus subject areas

  • Biomedical Engineering
  • Cellular and Molecular Neuroscience

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