A three-dimensional and sensitive bioassay based on nanostructured quartz combined with viral nanoparticles

Jong Hwan Lee; Jung Suk Kim; Jin Seung Park; Wonbae Lee; Kyung Eun Lee; Sung Sik Han; Kyu Back Lee; Jeewon Lee

doi:10.1002/adfm.200902054

A three-dimensional and sensitive bioassay based on nanostructured quartz combined with viral nanoparticles

Jong Hwan Lee, Jung Suk Kim, Jin Seung Park, Wonbae Lee, Kyung Eun Lee, Sung Sik Han, Kyu Back Lee, Jeewon Lee

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

An effective mask-free method for fabricating high-aspect-ratio pillarlike nanostructures over a large area of a quartz surface via a simple O₂ and CF₄ two-step reactive ion etching (RIE) procedure is developed. The nanostructured quartz surfaces are successfully combined with the engineered viral particles derived from hepatitis B virus capsid, yielding a novel 3D assay system with attomolar sensitivity, which has great potential for use in sensitive and early detection of various disease markers.

Original language	English
Pages (from-to)	2004-2009
Number of pages	6
Journal	Advanced Functional Materials
Volume	20
Issue number	12
DOIs	https://doi.org/10.1002/adfm.200902054
Publication status	Published - 2010 Jun 23

ASJC Scopus subject areas

Chemistry(all)
Materials Science(all)
Condensed Matter Physics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/adfm.200902054

Cite this

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abstract = "An effective mask-free method for fabricating high-aspect-ratio pillarlike nanostructures over a large area of a quartz surface via a simple O2 and CF4 two-step reactive ion etching (RIE) procedure is developed. The nanostructured quartz surfaces are successfully combined with the engineered viral particles derived from hepatitis B virus capsid, yielding a novel 3D assay system with attomolar sensitivity, which has great potential for use in sensitive and early detection of various disease markers.",

author = "Lee, {Jong Hwan} and Kim, {Jung Suk} and Park, {Jin Seung} and Wonbae Lee and Lee, {Kyung Eun} and Han, {Sung Sik} and Lee, {Kyu Back} and Jeewon Lee",

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AU - Lee, Jong Hwan

AU - Kim, Jung Suk

AU - Park, Jin Seung

AU - Lee, Wonbae

AU - Lee, Kyung Eun

AU - Han, Sung Sik

AU - Lee, Kyu Back

AU - Lee, Jeewon

PY - 2010/6/23

Y1 - 2010/6/23

N2 - An effective mask-free method for fabricating high-aspect-ratio pillarlike nanostructures over a large area of a quartz surface via a simple O2 and CF4 two-step reactive ion etching (RIE) procedure is developed. The nanostructured quartz surfaces are successfully combined with the engineered viral particles derived from hepatitis B virus capsid, yielding a novel 3D assay system with attomolar sensitivity, which has great potential for use in sensitive and early detection of various disease markers.

AB - An effective mask-free method for fabricating high-aspect-ratio pillarlike nanostructures over a large area of a quartz surface via a simple O2 and CF4 two-step reactive ion etching (RIE) procedure is developed. The nanostructured quartz surfaces are successfully combined with the engineered viral particles derived from hepatitis B virus capsid, yielding a novel 3D assay system with attomolar sensitivity, which has great potential for use in sensitive and early detection of various disease markers.

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DO - 10.1002/adfm.200902054

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JO - Advanced Functional Materials

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IS - 12

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A three-dimensional and sensitive bioassay based on nanostructured quartz combined with viral nanoparticles

Abstract

ASJC Scopus subject areas

UN SDGs

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