A two-photon excited luminescence of water-soluble rhodamine-platinum(II) complex: Fluorescent probe specific for Hg2+ detection in live cell

Jun Feng Zhang; Chang Su Lim; Bong-Rae Cho; Jong Seung Kim

doi:10.1016/j.talanta.2010.10.016

A two-photon excited luminescence of water-soluble rhodamine-platinum(II) complex: Fluorescent probe specific for Hg²⁺ detection in live cell

Jun Feng Zhang, Chang Su Lim, Bong-Rae Cho, Jong Seung Kim

Research output: Contribution to journal › Article › peer-review

64 Citations (Scopus)

Abstract

The first example of cyclometalated platinum(II)-containing rhodamine probe (1) with two-photon induced luminescent properties was synthesized and investigated for mercury detection. A highly selective color change of 1, from light yellow to pink, is observed only in the presence of Hg²⁺ due to the formation of 1,3,4-oxadiazole ring in 2. This selectivity of Hg ²⁺ with color changes can be observed easily by the naked-eye. Meanwhile, a remarkable turn-on and selective 20-fold fluorescent enhancement of 1 upon binding with Hg²⁺ over the other tested metal ions was observed. The water-soluble probe 1 was successfully applied in the visualizing of the site of Hg²⁺ accumulation as well as estimating of trace amounts of mercury ions in live HeLa cells by two-photon microscopy.

Original language	English
Pages (from-to)	658-662
Number of pages	5
Journal	Talanta
Volume	83
Issue number	2
DOIs	https://doi.org/10.1016/j.talanta.2010.10.016
Publication status	Published - 2010 Dec 15

Keywords

Platinum(II) complex
Rhodamine
Two-photon miscroscopy

ASJC Scopus subject areas

Analytical Chemistry

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title = "A two-photon excited luminescence of water-soluble rhodamine-platinum(II) complex: Fluorescent probe specific for Hg2+ detection in live cell",

abstract = "The first example of cyclometalated platinum(II)-containing rhodamine probe (1) with two-photon induced luminescent properties was synthesized and investigated for mercury detection. A highly selective color change of 1, from light yellow to pink, is observed only in the presence of Hg2+ due to the formation of 1,3,4-oxadiazole ring in 2. This selectivity of Hg 2+ with color changes can be observed easily by the naked-eye. Meanwhile, a remarkable turn-on and selective 20-fold fluorescent enhancement of 1 upon binding with Hg2+ over the other tested metal ions was observed. The water-soluble probe 1 was successfully applied in the visualizing of the site of Hg2+ accumulation as well as estimating of trace amounts of mercury ions in live HeLa cells by two-photon microscopy.",

keywords = "Platinum(II) complex, Rhodamine, Two-photon miscroscopy",

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AU - Lim, Chang Su

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AU - Kim, Jong Seung

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