A two-photon fluorescent probe for calcium waves in living tissue

Hwan Myung Kim, Bo Ra Kim, Jin Hee Hong, Jin Sung Park, Kyoung Jin Lee, Bong-Rae Cho

Research output: Contribution to journalArticle

87 Citations (Scopus)

Abstract

(Figure Presented) Intracellular messaging: The novel two-photon fluorescent probe ACa1 can visualize calcium waves in cells and living tissue for a long period of time and without any mistargeting problems (see picture). The probe is capable of monitoring the calcium waves at a depth of about 150 μm in living tissues for more than 1100 s and with no photobleaching artifacts.

Original languageEnglish
Pages (from-to)7445-7448
Number of pages4
JournalAngewandte Chemie - International Edition
Volume46
Issue number39
DOIs
Publication statusPublished - 2007 Oct 16

Fingerprint

Fluorescent Dyes
Calcium
Photons
Tissue
Photobleaching
Monitoring

Keywords

  • Calcium
  • Fluorescence
  • Microscopy
  • Two-photon probes

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

A two-photon fluorescent probe for calcium waves in living tissue. / Kim, Hwan Myung; Kim, Bo Ra; Hong, Jin Hee; Park, Jin Sung; Lee, Kyoung Jin; Cho, Bong-Rae.

In: Angewandte Chemie - International Edition, Vol. 46, No. 39, 16.10.2007, p. 7445-7448.

Research output: Contribution to journalArticle

Kim, Hwan Myung ; Kim, Bo Ra ; Hong, Jin Hee ; Park, Jin Sung ; Lee, Kyoung Jin ; Cho, Bong-Rae. / A two-photon fluorescent probe for calcium waves in living tissue. In: Angewandte Chemie - International Edition. 2007 ; Vol. 46, No. 39. pp. 7445-7448.
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