A two-photon tracer for glucose uptake

Yu Shun Tian, Hyang Yeon Lee, Chang Su Lim, Jongmin Park, Hwan Myung Kim, Yoo Na Shin, Eun-Sun Kim, Hoon Jae Jeon, Seung Bum Park, Bong-Rae Cho

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

It takes two: Two-photon tracers (AG1, AG2) have been developed that can be excited by 780 nm fs laser pulses, can be easily loaded into cancer cells and tissues, show high photostability and negligible toxicity, and can visualize glucose uptake in living cells and tissues by two-photon microscopy (TPM). Moreover, AG2 can screen anticancer agents in cancer cells and cancer tissues at 75-150 mm depth by TPM.

Original languageEnglish
Pages (from-to)8027-8031
Number of pages5
JournalAngewandte Chemie - International Edition
Volume48
Issue number43
DOIs
Publication statusPublished - 2009 Oct 12

Fingerprint

Glucose
Photons
Cells
Tissue
Microscopic examination
Antineoplastic Agents
Toxicity
Laser pulses

Keywords

  • Antitumor agents
  • Fluorescent probes
  • Glucose
  • Imaging agents
  • Two-photon microscopy

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

Cite this

Tian, Y. S., Lee, H. Y., Lim, C. S., Park, J., Kim, H. M., Shin, Y. N., ... Cho, B-R. (2009). A two-photon tracer for glucose uptake. Angewandte Chemie - International Edition, 48(43), 8027-8031. https://doi.org/10.1002/anie.200901175

A two-photon tracer for glucose uptake. / Tian, Yu Shun; Lee, Hyang Yeon; Lim, Chang Su; Park, Jongmin; Kim, Hwan Myung; Shin, Yoo Na; Kim, Eun-Sun; Jeon, Hoon Jae; Park, Seung Bum; Cho, Bong-Rae.

In: Angewandte Chemie - International Edition, Vol. 48, No. 43, 12.10.2009, p. 8027-8031.

Research output: Contribution to journalArticle

Tian, YS, Lee, HY, Lim, CS, Park, J, Kim, HM, Shin, YN, Kim, E-S, Jeon, HJ, Park, SB & Cho, B-R 2009, 'A two-photon tracer for glucose uptake', Angewandte Chemie - International Edition, vol. 48, no. 43, pp. 8027-8031. https://doi.org/10.1002/anie.200901175
Tian YS, Lee HY, Lim CS, Park J, Kim HM, Shin YN et al. A two-photon tracer for glucose uptake. Angewandte Chemie - International Edition. 2009 Oct 12;48(43):8027-8031. https://doi.org/10.1002/anie.200901175
Tian, Yu Shun ; Lee, Hyang Yeon ; Lim, Chang Su ; Park, Jongmin ; Kim, Hwan Myung ; Shin, Yoo Na ; Kim, Eun-Sun ; Jeon, Hoon Jae ; Park, Seung Bum ; Cho, Bong-Rae. / A two-photon tracer for glucose uptake. In: Angewandte Chemie - International Edition. 2009 ; Vol. 48, No. 43. pp. 8027-8031.
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