A wireless implantable switched-capacitor based optogenetic stimulating system

Hyung Min Lee, Ki Yong Kwon, Wen Li, Maysam Ghovanloo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

15 Citations (Scopus)

Abstract

This paper presents a power-efficient implantable optogenetic interface using a wireless switched-capacitor based stimulating (SCS) system. The SCS efficiently charges storage capacitors directly from an inductive link and periodically discharges them into an array of micro-LEDs, providing high instantaneous power without affecting wireless link and system supply voltage. A custom-designed computer interface in LabVIEW environment wirelessly controls stimulation parameters through the inductive link, and an optrode array enables simultaneous neural recording along with optical stimulation. The 4-channel SCS system prototype has been implemented in a 0.35-μm CMOS process and combined with the optrode array. In vivo experiments involving light-induced local field potentials verified the efficacy of the SCS system. An implantable version of the SCS system with flexible hermetic sealing is under development for chronic experiments.

Original languageEnglish
Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages878-881
Number of pages4
ISBN (Electronic)9781424479290
DOIs
Publication statusPublished - 2014 Nov 2
Externally publishedYes
Event2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States
Duration: 2014 Aug 262014 Aug 30

Publication series

Name2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014

Other

Other2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
CountryUnited States
CityChicago
Period14/8/2614/8/30

Fingerprint

Optogenetics
Capacitors
Light
Capacitor storage
Interfaces (computer)
Telecommunication links
Light emitting diodes
Experiments
Hermetic
Electric potential

ASJC Scopus subject areas

  • Health Informatics
  • Computer Science Applications
  • Biomedical Engineering
  • Medicine(all)

Cite this

Lee, H. M., Kwon, K. Y., Li, W., & Ghovanloo, M. (2014). A wireless implantable switched-capacitor based optogenetic stimulating system. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 (pp. 878-881). [6943731] (2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2014.6943731

A wireless implantable switched-capacitor based optogenetic stimulating system. / Lee, Hyung Min; Kwon, Ki Yong; Li, Wen; Ghovanloo, Maysam.

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., 2014. p. 878-881 6943731 (2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lee, HM, Kwon, KY, Li, W & Ghovanloo, M 2014, A wireless implantable switched-capacitor based optogenetic stimulating system. in 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014., 6943731, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, Institute of Electrical and Electronics Engineers Inc., pp. 878-881, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, Chicago, United States, 14/8/26. https://doi.org/10.1109/EMBC.2014.6943731
Lee HM, Kwon KY, Li W, Ghovanloo M. A wireless implantable switched-capacitor based optogenetic stimulating system. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc. 2014. p. 878-881. 6943731. (2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014). https://doi.org/10.1109/EMBC.2014.6943731
Lee, Hyung Min ; Kwon, Ki Yong ; Li, Wen ; Ghovanloo, Maysam. / A wireless implantable switched-capacitor based optogenetic stimulating system. 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., 2014. pp. 878-881 (2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014).
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