On-the-fly localization of abstract memory states is vital for economical abstract interpretation of imperative programs. Such localization is sometimes called "abstract garbage collection" or "framing". In this article we present a new memory localization technique that is more effective than the conventional reachability-based approach. Our technique is based on a key observation that collecting the reachable memory parts is too conservative and the accessed parts are usually tiny subsets of the reachable. Our technique first estimates, by an efficient pre-analysis, the set of locations that will be accessed during the analysis of each code block. Then the main analysis uses the access-set results to trim the memory entries before analyzing code blocks. In experiments with an industrial-strength global C static analyzer, the technique is applied right before analyzing each procedure's body and reduces the average analysis time and memory by 92.1% and 71.2%, respectively, without sacrificing the analysis precision. Localizing more frequently such as at loop bodies and basic blocks as well as procedure bodies, the generalized localization additionally reduces analysis time by an average of 31.8%.