Acute Effects of Cigarette Smoking on Arterial Stiffness and Blood Pressure in Male Smokers With Hypertension

Moo Yong Rhee, Sang Hoon Na, Young Kwon Kim, Myoung Mook Lee, Hae-Young Kim

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

Background: Although the acute increase of arterial stiffness and blood pressure (BP) after cigarette smoking in healthy smokers is considered a possible mechanism of increased cardiovascular risk, the acute effect of smoking on arterial stiffness in hypertensive smokers is unknown. We investigated the acute effects of cigarette smoking on arterial stiffness and BP in hypertensive male smokers. Methods: Heart rate (HR), brachial and ankle BP, and pulse-wave velocity (PWV) were measured in 22 hypertensive male smokers (HTs) and in 30 normotensive male smokers (NTs) before and 5, 10, and 15 min after smoking one cigarette (nicotine content, 0.9 mg). Results: Smoking induced acute increases of HR, brachial BP, and heart-femoral PWV (hfPWV) in NTs and HTs (P < .05). Ankle systolic BP and femoral-ankle PWV were acutely increased in HTs (P < .05), but not in NTs. In HTs, brachial systolic BP and hfPWV at 15 min were higher than at baseline (P < .05). An acute increase of hfPWV in the HTs was significant (P = .025) after adjustment for total cholesterol, time-dependent HR, and brachial mean arterial pressure, but acute changes of other PWVs lost statistical significance. Conclusions: Cigarette smoking acutely increases aortic stiffness and BP in male smokers with hypertension, and the effects persist longer than in male smokers without hypertension.

Original languageEnglish
Pages (from-to)637-641
Number of pages5
JournalAmerican Journal of Hypertension
Volume20
Issue number6
DOIs
Publication statusPublished - 2007 Jun 1
Externally publishedYes

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Vascular Stiffness
Arterial Pressure
Smoking
Thigh
Blood Pressure
Hypertension
Pulse Wave Analysis
Arm
Ankle
Heart Rate
Nicotine
Cholesterol

Keywords

  • arterial stiffness
  • hypertension
  • Smoking

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Acute Effects of Cigarette Smoking on Arterial Stiffness and Blood Pressure in Male Smokers With Hypertension. / Rhee, Moo Yong; Na, Sang Hoon; Kim, Young Kwon; Lee, Myoung Mook; Kim, Hae-Young.

In: American Journal of Hypertension, Vol. 20, No. 6, 01.06.2007, p. 637-641.

Research output: Contribution to journalArticle

Rhee, Moo Yong ; Na, Sang Hoon ; Kim, Young Kwon ; Lee, Myoung Mook ; Kim, Hae-Young. / Acute Effects of Cigarette Smoking on Arterial Stiffness and Blood Pressure in Male Smokers With Hypertension. In: American Journal of Hypertension. 2007 ; Vol. 20, No. 6. pp. 637-641.
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N2 - Background: Although the acute increase of arterial stiffness and blood pressure (BP) after cigarette smoking in healthy smokers is considered a possible mechanism of increased cardiovascular risk, the acute effect of smoking on arterial stiffness in hypertensive smokers is unknown. We investigated the acute effects of cigarette smoking on arterial stiffness and BP in hypertensive male smokers. Methods: Heart rate (HR), brachial and ankle BP, and pulse-wave velocity (PWV) were measured in 22 hypertensive male smokers (HTs) and in 30 normotensive male smokers (NTs) before and 5, 10, and 15 min after smoking one cigarette (nicotine content, 0.9 mg). Results: Smoking induced acute increases of HR, brachial BP, and heart-femoral PWV (hfPWV) in NTs and HTs (P < .05). Ankle systolic BP and femoral-ankle PWV were acutely increased in HTs (P < .05), but not in NTs. In HTs, brachial systolic BP and hfPWV at 15 min were higher than at baseline (P < .05). An acute increase of hfPWV in the HTs was significant (P = .025) after adjustment for total cholesterol, time-dependent HR, and brachial mean arterial pressure, but acute changes of other PWVs lost statistical significance. Conclusions: Cigarette smoking acutely increases aortic stiffness and BP in male smokers with hypertension, and the effects persist longer than in male smokers without hypertension.

AB - Background: Although the acute increase of arterial stiffness and blood pressure (BP) after cigarette smoking in healthy smokers is considered a possible mechanism of increased cardiovascular risk, the acute effect of smoking on arterial stiffness in hypertensive smokers is unknown. We investigated the acute effects of cigarette smoking on arterial stiffness and BP in hypertensive male smokers. Methods: Heart rate (HR), brachial and ankle BP, and pulse-wave velocity (PWV) were measured in 22 hypertensive male smokers (HTs) and in 30 normotensive male smokers (NTs) before and 5, 10, and 15 min after smoking one cigarette (nicotine content, 0.9 mg). Results: Smoking induced acute increases of HR, brachial BP, and heart-femoral PWV (hfPWV) in NTs and HTs (P < .05). Ankle systolic BP and femoral-ankle PWV were acutely increased in HTs (P < .05), but not in NTs. In HTs, brachial systolic BP and hfPWV at 15 min were higher than at baseline (P < .05). An acute increase of hfPWV in the HTs was significant (P = .025) after adjustment for total cholesterol, time-dependent HR, and brachial mean arterial pressure, but acute changes of other PWVs lost statistical significance. Conclusions: Cigarette smoking acutely increases aortic stiffness and BP in male smokers with hypertension, and the effects persist longer than in male smokers without hypertension.

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