Acute high-frequency rTMS of the left dorsolateral prefrontal cortex and attentional control in healthy young men

Ji Hee Hwang, Sang Hee Kim, Chang Soo Park, Seong Ae Bang, Sang Eun Kim

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Previous studies have shown that high-frequency repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex induces neuromodulation in prefrontal and striatal regions. We hypothesized that high-frequency rTMS over the dorsolateral prefrontal cortex would influence attentional control, which has been associated with neural activity in the same region. Seventeen healthy young men volunteered to participate in a sham-controlled rTMS study. Participants received both rTMS and sham stimulation on separate days and the Conners' continuous performance test was used to assess response inhibition and attentional vigilance. Results indicated that participants showed fewer commission errors during trials after rTMS as compared with sham stimulation, at longer interstimulus intervals (ISIs), which suggests that high-frequency rTMS may have the potential to improve response inhibition. This finding contributes to the understanding of the relationship between the dorsolateral prefrontal cortex and attentional control and suggests possible therapeutic applications for high-frequency rTMS.

Original languageEnglish
Pages (from-to)152-158
Number of pages7
JournalBrain Research
Volume1329
DOIs
Publication statusPublished - 2010 May 6

Fingerprint

Transcranial Magnetic Stimulation
Prefrontal Cortex
Corpus Striatum

Keywords

  • Attentional control
  • Conners' CPT
  • Dorsolateral prefrontal cortex
  • rTMS

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology
  • Developmental Biology
  • Molecular Biology

Cite this

Acute high-frequency rTMS of the left dorsolateral prefrontal cortex and attentional control in healthy young men. / Hwang, Ji Hee; Kim, Sang Hee; Park, Chang Soo; Bang, Seong Ae; Kim, Sang Eun.

In: Brain Research, Vol. 1329, 06.05.2010, p. 152-158.

Research output: Contribution to journalArticle

Hwang, Ji Hee ; Kim, Sang Hee ; Park, Chang Soo ; Bang, Seong Ae ; Kim, Sang Eun. / Acute high-frequency rTMS of the left dorsolateral prefrontal cortex and attentional control in healthy young men. In: Brain Research. 2010 ; Vol. 1329. pp. 152-158.
@article{d381529d42df4e0799972c2c70b44bce,
title = "Acute high-frequency rTMS of the left dorsolateral prefrontal cortex and attentional control in healthy young men",
abstract = "Previous studies have shown that high-frequency repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex induces neuromodulation in prefrontal and striatal regions. We hypothesized that high-frequency rTMS over the dorsolateral prefrontal cortex would influence attentional control, which has been associated with neural activity in the same region. Seventeen healthy young men volunteered to participate in a sham-controlled rTMS study. Participants received both rTMS and sham stimulation on separate days and the Conners' continuous performance test was used to assess response inhibition and attentional vigilance. Results indicated that participants showed fewer commission errors during trials after rTMS as compared with sham stimulation, at longer interstimulus intervals (ISIs), which suggests that high-frequency rTMS may have the potential to improve response inhibition. This finding contributes to the understanding of the relationship between the dorsolateral prefrontal cortex and attentional control and suggests possible therapeutic applications for high-frequency rTMS.",
keywords = "Attentional control, Conners' CPT, Dorsolateral prefrontal cortex, rTMS",
author = "Hwang, {Ji Hee} and Kim, {Sang Hee} and Park, {Chang Soo} and Bang, {Seong Ae} and Kim, {Sang Eun}",
year = "2010",
month = "5",
day = "6",
doi = "10.1016/j.brainres.2010.03.013",
language = "English",
volume = "1329",
pages = "152--158",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",

}

TY - JOUR

T1 - Acute high-frequency rTMS of the left dorsolateral prefrontal cortex and attentional control in healthy young men

AU - Hwang, Ji Hee

AU - Kim, Sang Hee

AU - Park, Chang Soo

AU - Bang, Seong Ae

AU - Kim, Sang Eun

PY - 2010/5/6

Y1 - 2010/5/6

N2 - Previous studies have shown that high-frequency repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex induces neuromodulation in prefrontal and striatal regions. We hypothesized that high-frequency rTMS over the dorsolateral prefrontal cortex would influence attentional control, which has been associated with neural activity in the same region. Seventeen healthy young men volunteered to participate in a sham-controlled rTMS study. Participants received both rTMS and sham stimulation on separate days and the Conners' continuous performance test was used to assess response inhibition and attentional vigilance. Results indicated that participants showed fewer commission errors during trials after rTMS as compared with sham stimulation, at longer interstimulus intervals (ISIs), which suggests that high-frequency rTMS may have the potential to improve response inhibition. This finding contributes to the understanding of the relationship between the dorsolateral prefrontal cortex and attentional control and suggests possible therapeutic applications for high-frequency rTMS.

AB - Previous studies have shown that high-frequency repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex induces neuromodulation in prefrontal and striatal regions. We hypothesized that high-frequency rTMS over the dorsolateral prefrontal cortex would influence attentional control, which has been associated with neural activity in the same region. Seventeen healthy young men volunteered to participate in a sham-controlled rTMS study. Participants received both rTMS and sham stimulation on separate days and the Conners' continuous performance test was used to assess response inhibition and attentional vigilance. Results indicated that participants showed fewer commission errors during trials after rTMS as compared with sham stimulation, at longer interstimulus intervals (ISIs), which suggests that high-frequency rTMS may have the potential to improve response inhibition. This finding contributes to the understanding of the relationship between the dorsolateral prefrontal cortex and attentional control and suggests possible therapeutic applications for high-frequency rTMS.

KW - Attentional control

KW - Conners' CPT

KW - Dorsolateral prefrontal cortex

KW - rTMS

UR - http://www.scopus.com/inward/record.url?scp=77950860968&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77950860968&partnerID=8YFLogxK

U2 - 10.1016/j.brainres.2010.03.013

DO - 10.1016/j.brainres.2010.03.013

M3 - Article

C2 - 20226772

AN - SCOPUS:77950860968

VL - 1329

SP - 152

EP - 158

JO - Brain Research

JF - Brain Research

SN - 0006-8993

ER -