Acute Kidney Injury and Hepatorenal Syndrome

Moon Young Kim, Yeon Seok Seo

Research output: Contribution to journalReview article

Abstract

Acute kidney injury (AKI) is common in patients with liver cirrhosis, occurring in 13-20% of patients hospitalized with decompensated cirrhosis, and is significantly associated with the prognosis. The development and progression of AKI is an independent predictive factor for mortality in these patients. If AKI develops, the renal function declines progressively even if AKI is improved later, the patients have a poorer prognosis compared to those who have not developed AKI. In addition, in patients without appropriate treatment or no improvement with the initial treatment, AKI often progress to hepatorenal syndrome (HRS), which is associated with significant morbidity and mortality. Therefore, early detection and appropriate management for the development of AKI is very important in these patients. Recently, there have been significant revisions in the diagnostic criteria and treatment of AKI and HRS; this manuscript reviews these changes.

Original languageEnglish
Pages (from-to)64-73
Number of pages10
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume72
Issue number2
DOIs
Publication statusPublished - 2018 Aug 25

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Hepatorenal Syndrome
Acute Kidney Injury
Mortality
Liver Cirrhosis
Fibrosis
Therapeutics
Morbidity
Kidney

Keywords

  • Acute kidney injury
  • Hepatorenal syndrome
  • Hypertension portal
  • Liver cirrhosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Acute Kidney Injury and Hepatorenal Syndrome. / Kim, Moon Young; Seo, Yeon Seok.

In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, Vol. 72, No. 2, 25.08.2018, p. 64-73.

Research output: Contribution to journalReview article

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