Acute myocarditis associated with cardiac amyloidosis manifesting as transient complete atrioventricular block and slow ventricular tachycardia

Hong Euy Lim, Hui Nam Pak, Young Hoon Kim

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

This is the first report of conduction system disturbances and slow ventricular tachycardia (VT), related to acute myocarditis associated with cardiac amyloidosis. A 57-year-old female was presented with chest pain and pre-syncope after flu-like symptoms, and was promptly diagnosed with acute myocarditis. The initial electrocardiogram (ECG) revealed complete atrioventricular (AV) block, and transient slow VT was observed after an atropine injection (0.5 mg). This AV conduction disturbance persisted for 12 days, and spontaneously resolved. Left ventricular function was relatively well preserved, and an endomyocardial biopsy revealed acute myocardial inflammation and underlying amyloid deposits. A His-bundle recording, taken 6 weeks after the initial manifestation, indicated normal AV nodal conduction. Endomyocardial biopsies have proven helpful with regard to the diagnosis of acute myocarditis superimposed on amyloidosis, in patients who present with conduction disorder and relatively preserved ventricular function, as was seen in this case.

Original languageEnglish
Pages (from-to)395-397
Number of pages3
JournalInternational Journal of Cardiology
Volume109
Issue number3
DOIs
Publication statusPublished - 2006 May 24

Fingerprint

Accelerated Idioventricular Rhythm
Atrioventricular Block
Myocarditis
Amyloidosis
Biopsy
Bundle of His
Ventricular Function
Amyloid Plaques
Syncope
Chest Pain
Atropine
Left Ventricular Function
Electrocardiography
Inflammation
Injections

Keywords

  • Acute myocarditis
  • Atrioventricular block
  • Cardiac amyloidosis
  • Slow ventricular tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Acute myocarditis associated with cardiac amyloidosis manifesting as transient complete atrioventricular block and slow ventricular tachycardia",
abstract = "This is the first report of conduction system disturbances and slow ventricular tachycardia (VT), related to acute myocarditis associated with cardiac amyloidosis. A 57-year-old female was presented with chest pain and pre-syncope after flu-like symptoms, and was promptly diagnosed with acute myocarditis. The initial electrocardiogram (ECG) revealed complete atrioventricular (AV) block, and transient slow VT was observed after an atropine injection (0.5 mg). This AV conduction disturbance persisted for 12 days, and spontaneously resolved. Left ventricular function was relatively well preserved, and an endomyocardial biopsy revealed acute myocardial inflammation and underlying amyloid deposits. A His-bundle recording, taken 6 weeks after the initial manifestation, indicated normal AV nodal conduction. Endomyocardial biopsies have proven helpful with regard to the diagnosis of acute myocarditis superimposed on amyloidosis, in patients who present with conduction disorder and relatively preserved ventricular function, as was seen in this case.",
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AU - Pak, Hui Nam

AU - Kim, Young Hoon

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N2 - This is the first report of conduction system disturbances and slow ventricular tachycardia (VT), related to acute myocarditis associated with cardiac amyloidosis. A 57-year-old female was presented with chest pain and pre-syncope after flu-like symptoms, and was promptly diagnosed with acute myocarditis. The initial electrocardiogram (ECG) revealed complete atrioventricular (AV) block, and transient slow VT was observed after an atropine injection (0.5 mg). This AV conduction disturbance persisted for 12 days, and spontaneously resolved. Left ventricular function was relatively well preserved, and an endomyocardial biopsy revealed acute myocardial inflammation and underlying amyloid deposits. A His-bundle recording, taken 6 weeks after the initial manifestation, indicated normal AV nodal conduction. Endomyocardial biopsies have proven helpful with regard to the diagnosis of acute myocarditis superimposed on amyloidosis, in patients who present with conduction disorder and relatively preserved ventricular function, as was seen in this case.

AB - This is the first report of conduction system disturbances and slow ventricular tachycardia (VT), related to acute myocarditis associated with cardiac amyloidosis. A 57-year-old female was presented with chest pain and pre-syncope after flu-like symptoms, and was promptly diagnosed with acute myocarditis. The initial electrocardiogram (ECG) revealed complete atrioventricular (AV) block, and transient slow VT was observed after an atropine injection (0.5 mg). This AV conduction disturbance persisted for 12 days, and spontaneously resolved. Left ventricular function was relatively well preserved, and an endomyocardial biopsy revealed acute myocardial inflammation and underlying amyloid deposits. A His-bundle recording, taken 6 weeks after the initial manifestation, indicated normal AV nodal conduction. Endomyocardial biopsies have proven helpful with regard to the diagnosis of acute myocarditis superimposed on amyloidosis, in patients who present with conduction disorder and relatively preserved ventricular function, as was seen in this case.

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KW - Slow ventricular tachycardia

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