Abstract
Over the past decade, stem cell therapy has been extensively studied for clinical application for heart diseases. Among various stem cells, adipose tissue-derived stem cell (ADSC) is still an attractive stem cell resource due to its abundance and easy accessibility. In vitro studies showed the multipotent differentiation potentials of ADSC, even differentiation into cardiomyocytes. Many pre-clinical animal studies have also demonstrated promising therapeutic results of ADSC. Furthermore, there were several clinical trials showing the positive results in acute myocardial infarction using ADSC. The present article covers the brief introduction, the suggested therapeutic mechanisms, application methods including cell dose and delivery, and human clinical trials of ADSC for myocardial regeneration.
| Original language | English |
|---|---|
| Pages (from-to) | 151-159 |
| Number of pages | 9 |
| Journal | Korean Circulation Journal |
| Volume | 47 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2017 Mar 1 |
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Keywords
- Adipose tissue
- Myocardium
- Regeneration
- Stem cell
ASJC Scopus subject areas
- Internal Medicine
- Cardiology and Cardiovascular Medicine
Cite this
Adipose tissue-derived stem cells for myocardial regeneration. / Joo, Hyung Joon; Kim, Jong Ho; Hong, Soon Jun.
In: Korean Circulation Journal, Vol. 47, No. 2, 01.03.2017, p. 151-159.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Adipose tissue-derived stem cells for myocardial regeneration
AU - Joo, Hyung Joon
AU - Kim, Jong Ho
AU - Hong, Soon Jun
PY - 2017/3/1
Y1 - 2017/3/1
N2 - Over the past decade, stem cell therapy has been extensively studied for clinical application for heart diseases. Among various stem cells, adipose tissue-derived stem cell (ADSC) is still an attractive stem cell resource due to its abundance and easy accessibility. In vitro studies showed the multipotent differentiation potentials of ADSC, even differentiation into cardiomyocytes. Many pre-clinical animal studies have also demonstrated promising therapeutic results of ADSC. Furthermore, there were several clinical trials showing the positive results in acute myocardial infarction using ADSC. The present article covers the brief introduction, the suggested therapeutic mechanisms, application methods including cell dose and delivery, and human clinical trials of ADSC for myocardial regeneration.
AB - Over the past decade, stem cell therapy has been extensively studied for clinical application for heart diseases. Among various stem cells, adipose tissue-derived stem cell (ADSC) is still an attractive stem cell resource due to its abundance and easy accessibility. In vitro studies showed the multipotent differentiation potentials of ADSC, even differentiation into cardiomyocytes. Many pre-clinical animal studies have also demonstrated promising therapeutic results of ADSC. Furthermore, there were several clinical trials showing the positive results in acute myocardial infarction using ADSC. The present article covers the brief introduction, the suggested therapeutic mechanisms, application methods including cell dose and delivery, and human clinical trials of ADSC for myocardial regeneration.
KW - Adipose tissue
KW - Myocardium
KW - Regeneration
KW - Stem cell
UR - http://www.scopus.com/inward/record.url?scp=85017405118&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85017405118&partnerID=8YFLogxK
U2 - 10.4070/kcj.2016.0207
DO - 10.4070/kcj.2016.0207
M3 - Review article
AN - SCOPUS:85017405118
VL - 47
SP - 151
EP - 159
JO - Korean Circulation Journal
JF - Korean Circulation Journal
SN - 1738-5520
IS - 2
ER -