Adipose tissue-derived stem cells for myocardial regeneration

Hyung Joon Joo; Jong Ho Kim; Soon Jun Hong

doi:10.4070/kcj.2016.0207

Adipose tissue-derived stem cells for myocardial regeneration

Hyung Joon Joo, Jong Ho Kim, Soon Jun Hong

Department of Cardiology

Research output: Contribution to journal › Review article

14 Citations (Scopus)

Abstract

Over the past decade, stem cell therapy has been extensively studied for clinical application for heart diseases. Among various stem cells, adipose tissue-derived stem cell (ADSC) is still an attractive stem cell resource due to its abundance and easy accessibility. In vitro studies showed the multipotent differentiation potentials of ADSC, even differentiation into cardiomyocytes. Many pre-clinical animal studies have also demonstrated promising therapeutic results of ADSC. Furthermore, there were several clinical trials showing the positive results in acute myocardial infarction using ADSC. The present article covers the brief introduction, the suggested therapeutic mechanisms, application methods including cell dose and delivery, and human clinical trials of ADSC for myocardial regeneration.

Original language	English
Pages (from-to)	151-159
Number of pages	9
Journal	Korean Circulation Journal
Volume	47
Issue number	2
DOIs	https://doi.org/10.4070/kcj.2016.0207
Publication status	Published - 2017 Mar

Keywords

Adipose tissue
Myocardium
Regeneration
Stem cell

ASJC Scopus subject areas

Internal Medicine
Cardiology and Cardiovascular Medicine

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Joo, H. J., Kim, J. H., & Hong, S. J. (2017). Adipose tissue-derived stem cells for myocardial regeneration. Korean Circulation Journal, 47(2), 151-159. https://doi.org/10.4070/kcj.2016.0207

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