Adipose tissue-derived stem cells for myocardial regeneration

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

Over the past decade, stem cell therapy has been extensively studied for clinical application for heart diseases. Among various stem cells, adipose tissue-derived stem cell (ADSC) is still an attractive stem cell resource due to its abundance and easy accessibility. In vitro studies showed the multipotent differentiation potentials of ADSC, even differentiation into cardiomyocytes. Many pre-clinical animal studies have also demonstrated promising therapeutic results of ADSC. Furthermore, there were several clinical trials showing the positive results in acute myocardial infarction using ADSC. The present article covers the brief introduction, the suggested therapeutic mechanisms, application methods including cell dose and delivery, and human clinical trials of ADSC for myocardial regeneration.

Original languageEnglish
Pages (from-to)151-159
Number of pages9
JournalKorean Circulation Journal
Volume47
Issue number2
DOIs
Publication statusPublished - 2017 Mar 1

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Keywords

  • Adipose tissue
  • Myocardium
  • Regeneration
  • Stem cell

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

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