Adipose tissue-derived stem cells for myocardial regeneration

Hyung Joon Joo, Jong Ho Kim, Soon Jun Hong

    Research output: Contribution to journalReview articlepeer-review

    18 Citations (Scopus)

    Abstract

    Over the past decade, stem cell therapy has been extensively studied for clinical application for heart diseases. Among various stem cells, adipose tissue-derived stem cell (ADSC) is still an attractive stem cell resource due to its abundance and easy accessibility. In vitro studies showed the multipotent differentiation potentials of ADSC, even differentiation into cardiomyocytes. Many pre-clinical animal studies have also demonstrated promising therapeutic results of ADSC. Furthermore, there were several clinical trials showing the positive results in acute myocardial infarction using ADSC. The present article covers the brief introduction, the suggested therapeutic mechanisms, application methods including cell dose and delivery, and human clinical trials of ADSC for myocardial regeneration.

    Original languageEnglish
    Pages (from-to)151-159
    Number of pages9
    JournalKorean Circulation Journal
    Volume47
    Issue number2
    DOIs
    Publication statusPublished - 2017 Mar

    Keywords

    • Adipose tissue
    • Myocardium
    • Regeneration
    • Stem cell

    ASJC Scopus subject areas

    • Internal Medicine
    • Cardiology and Cardiovascular Medicine

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