TY - JOUR
T1 - Adsorbed Water Structure on Acrylate-Based Biocompatible Polymer Surface
AU - Mondal, Saptarsi
AU - Kang, Jooyoun
AU - Park, Kwanghee
AU - Lim, Jong Min
AU - Ha, Jeong Hyon
AU - Kwak, Kyungwon
AU - Cho, Minhaeng
N1 - Funding Information:
This work was supported by the Institute for Basic Science (IBS-R023-D1) (M.C.) and the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (NRF-2020R1A2C2010675) (K.K.).
Publisher Copyright:
© 2021 American Chemical Society.
PY - 2021/9/30
Y1 - 2021/9/30
N2 - The role of water in the excellent biocompatibility of the acrylate-based polymers widely used for antibiofouling coating material has been realized previously. Here, we report femtosecond mid-infrared pump-probe spectroscopy of the OD stretch band of HOD molecule adsorbed on highly biocompatible poly(2-methoxyethyl) acrylate [PMEA] and poorly biocompatible poly(2-phenoxyethyl) acrylate [PPEA], both of which reveal that there are two water species with significantly different vibrational lifetime. PMEA interacts more strongly with water than PPEA through the H-bonding interaction between carbonyl (C=O) and water. The vibrational lifetime of the OD stretch in PPEA is notably longer by factors of 3 and 7 than those in PMEA and bulk water, respectively. The IR-pump visible-probe photothermal imaging further unravels substantial spatial overlap between polymer CO group and water for hydrated PMEA and a significant difference in surface morphology than those in PPEA, which exhibits the underlying relationships among polymer-water interaction, surface morphology, and biocompatibility.
AB - The role of water in the excellent biocompatibility of the acrylate-based polymers widely used for antibiofouling coating material has been realized previously. Here, we report femtosecond mid-infrared pump-probe spectroscopy of the OD stretch band of HOD molecule adsorbed on highly biocompatible poly(2-methoxyethyl) acrylate [PMEA] and poorly biocompatible poly(2-phenoxyethyl) acrylate [PPEA], both of which reveal that there are two water species with significantly different vibrational lifetime. PMEA interacts more strongly with water than PPEA through the H-bonding interaction between carbonyl (C=O) and water. The vibrational lifetime of the OD stretch in PPEA is notably longer by factors of 3 and 7 than those in PMEA and bulk water, respectively. The IR-pump visible-probe photothermal imaging further unravels substantial spatial overlap between polymer CO group and water for hydrated PMEA and a significant difference in surface morphology than those in PPEA, which exhibits the underlying relationships among polymer-water interaction, surface morphology, and biocompatibility.
UR - http://www.scopus.com/inward/record.url?scp=85116058656&partnerID=8YFLogxK
U2 - 10.1021/acs.jpclett.1c02491
DO - 10.1021/acs.jpclett.1c02491
M3 - Article
C2 - 34534434
AN - SCOPUS:85116058656
SN - 1948-7185
VL - 12
SP - 9275
EP - 9282
JO - Journal of Physical Chemistry Letters
JF - Journal of Physical Chemistry Letters
IS - 38
ER -