Adult neurogenesis in the central and peripheral nervous systems

Hyun Jung Kim, Woong Sun

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Neurogenesis occurs during embryonic development and continues throughout adulthood. Although spontaneous adult neurogenesis is restricted to selective germinal regions, including the subventricular zone and dentate gyrus of the hippocampus, neural stem cells (NSCs) are widely distributed in the central and peripheral nervous systems. Besides their ability to integrate into existing neural networks during physiological conditions, NSCs also proliferate and differentiate in response to injury, thus promising the potential use of endogenous NSCs for the treatment of neuropathological conditions. In this review, we discuss recent progress in the understanding of adult neurogenesis in the brain and peripheral nervous system.

Original languageEnglish
Pages (from-to)57-61
Number of pages5
JournalInternational Neurourology Journal
Volume16
Issue number2
DOIs
Publication statusPublished - 2012 Jun 1

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Keywords

  • Adult stem cells
  • Central nervous system
  • Neural stem cells
  • Neurogenesis
  • Peripheral nervous system

ASJC Scopus subject areas

  • Clinical Neurology
  • Urology
  • Neurology

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