TY - JOUR
T1 - Adult neurogenesis in the central and peripheral nervous systems
AU - Kim, Hyun Jung
AU - Sun, Woong
N1 - Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.
PY - 2012/6
Y1 - 2012/6
N2 - Neurogenesis occurs during embryonic development and continues throughout adulthood. Although spontaneous adult neurogenesis is restricted to selective germinal regions, including the subventricular zone and dentate gyrus of the hippocampus, neural stem cells (NSCs) are widely distributed in the central and peripheral nervous systems. Besides their ability to integrate into existing neural networks during physiological conditions, NSCs also proliferate and differentiate in response to injury, thus promising the potential use of endogenous NSCs for the treatment of neuropathological conditions. In this review, we discuss recent progress in the understanding of adult neurogenesis in the brain and peripheral nervous system.
AB - Neurogenesis occurs during embryonic development and continues throughout adulthood. Although spontaneous adult neurogenesis is restricted to selective germinal regions, including the subventricular zone and dentate gyrus of the hippocampus, neural stem cells (NSCs) are widely distributed in the central and peripheral nervous systems. Besides their ability to integrate into existing neural networks during physiological conditions, NSCs also proliferate and differentiate in response to injury, thus promising the potential use of endogenous NSCs for the treatment of neuropathological conditions. In this review, we discuss recent progress in the understanding of adult neurogenesis in the brain and peripheral nervous system.
KW - Adult stem cells
KW - Central nervous system
KW - Neural stem cells
KW - Neurogenesis
KW - Peripheral nervous system
UR - http://www.scopus.com/inward/record.url?scp=84866942143&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84866942143&partnerID=8YFLogxK
U2 - 10.5213/inj.2012.16.2.57
DO - 10.5213/inj.2012.16.2.57
M3 - Review article
C2 - 22816045
AN - SCOPUS:84866942143
VL - 16
SP - 57
EP - 61
JO - International Neurourology Journal
JF - International Neurourology Journal
SN - 2093-4777
IS - 2
ER -