Age- and flow-dependency of salivary viscoelasticity

E. Zussman, Alexander Yarin, R. M. Nagler

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Measuring salivary viscoelasticity (by relaxation times) is of paramount importance, since salivary rheology behavior has been associated with the development of oral disease conditions (such as dental caries) in animal and human model studies. In addition, novel and improved methods to evaluate salivary distribution and lubrication are of clinical interest. We used a novel method for measuring the viscoelasticity of saliva secreted from the different glands, at rest or under stimulation and at different ages, all conditions where different viscoelastic properties might be clinically important. Submandibular/sublingual salivary viscoelasticity was significantly higher than that of parotid saliva, especially under stimulation. In addition, an age-related reduction in flow rate (by 62%) was demonstrated, accompanied by an increase in both relaxation time (by 54%) and protein (by 48%). Increased salivary viscoelasticity results in compromised salivary rheology and lubrication properties, which may render the oral cavities of the elderly and other xerostomic persons more vulnerable.

Original languageEnglish
Pages (from-to)281-285
Number of pages5
JournalJournal of Dental Research
Volume86
Issue number3
DOIs
Publication statusPublished - 2007 Mar 1
Externally publishedYes

Fingerprint

Lubrication
Rheology
Saliva
Mouth Diseases
Hospital Distribution Systems
Dental Caries
Mouth
Animal Models
Proteins
Dependency (Psychology)

Keywords

  • Elongational viscosity
  • Relaxation time
  • Rheology
  • Saliva
  • Viscoelasticity

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Age- and flow-dependency of salivary viscoelasticity. / Zussman, E.; Yarin, Alexander; Nagler, R. M.

In: Journal of Dental Research, Vol. 86, No. 3, 01.03.2007, p. 281-285.

Research output: Contribution to journalArticle

Zussman, E. ; Yarin, Alexander ; Nagler, R. M. / Age- and flow-dependency of salivary viscoelasticity. In: Journal of Dental Research. 2007 ; Vol. 86, No. 3. pp. 281-285.
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