Allosteric supramolecular triple-layer catalysts

Hyo Jae Yoon, Junpei Kuwabara, Jun Hyun Kim, Chad A. Mirkin

Research output: Contribution to journalArticle

186 Citations (Scopus)

Abstract

Allosteric regulation of organometallic catalysts could allow for greater control over reactions. We report an allosteric supramolecular structure in which a monometallic catalytic site has been buried in the middle layer of a triple-layer complex. Small molecules and elemental anions can open and close this complex and reversibly expose and conceal the catalytic center. The ring-opening polymerization of ε-caprolactone can be turned on by the in situ opening of the triple-layer complex and then completely turned off by reforming it through the abstraction of Cl-, the allosteric effector agent, without appreciable loss of catalytic activity. This process can regulate the molecular weights of the resulting polymers.

Original languageEnglish
Pages (from-to)66-69
Number of pages4
JournalScience
Volume330
Issue number6000
DOIs
Publication statusPublished - 2010 Oct 1
Externally publishedYes

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Allosteric Regulation
Polymerization
Anions
Catalytic Domain
Polymers
Molecular Weight
caprolactone

ASJC Scopus subject areas

  • General

Cite this

Yoon, H. J., Kuwabara, J., Kim, J. H., & Mirkin, C. A. (2010). Allosteric supramolecular triple-layer catalysts. Science, 330(6000), 66-69. https://doi.org/10.1126/science.1193928

Allosteric supramolecular triple-layer catalysts. / Yoon, Hyo Jae; Kuwabara, Junpei; Kim, Jun Hyun; Mirkin, Chad A.

In: Science, Vol. 330, No. 6000, 01.10.2010, p. 66-69.

Research output: Contribution to journalArticle

Yoon, HJ, Kuwabara, J, Kim, JH & Mirkin, CA 2010, 'Allosteric supramolecular triple-layer catalysts', Science, vol. 330, no. 6000, pp. 66-69. https://doi.org/10.1126/science.1193928
Yoon, Hyo Jae ; Kuwabara, Junpei ; Kim, Jun Hyun ; Mirkin, Chad A. / Allosteric supramolecular triple-layer catalysts. In: Science. 2010 ; Vol. 330, No. 6000. pp. 66-69.
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