Abstract
The sodium/iodide symporter (NIS) is a membrane glycoprotein that mediates active I uptake during the treatment of cancer of the thyroid gland and extrathyroidal tissues. NIS gene transfection, a gene-therapy modality, has been introduced in many types of cancer, such as prostate cancer and breast cancer, and has demonstrated a high potential for the treatment of non-thyroidal cancers. To investigate the pattern of NIS gene expression and provide evidence of its beneficial effects in human anaplastic cancer ARO cells by using a radioactive complementary DNA (cDNA) microarray.
Original language | English |
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Pages (from-to) | 1155-1162 |
Number of pages | 8 |
Journal | Nuclear Medicine Communications |
Volume | 26 |
Issue number | 12 |
DOIs | |
Publication status | Published - 2005 Dec |
Keywords
- CDNA microarray
- Human anaplastic cancer ARO cells
- PTP family
- Ras oncogene family
- Sodium/iodide symporter (NIS)
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging