Abstract
The sodium/iodide symporter (NIS) is a membrane glycoprotein that mediates active I uptake during the treatment of cancer of the thyroid gland and extrathyroidal tissues. NIS gene transfection, a gene-therapy modality, has been introduced in many types of cancer, such as prostate cancer and breast cancer, and has demonstrated a high potential for the treatment of non-thyroidal cancers. To investigate the pattern of NIS gene expression and provide evidence of its beneficial effects in human anaplastic cancer ARO cells by using a radioactive complementary DNA (cDNA) microarray.
| Original language | English |
|---|---|
| Pages (from-to) | 1155-1162 |
| Number of pages | 8 |
| Journal | Nuclear Medicine Communications |
| Volume | 26 |
| Issue number | 12 |
| Publication status | Published - 2005 |
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Keywords
- CDNA microarray
- Human anaplastic cancer ARO cells
- PTP family
- Ras oncogene family
- Sodium/iodide symporter (NIS)
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Altered gene expression profiles by sodium/iodide symporter gene transfection in a human anaplastic thyroid carcinoma cell line using a radioactive complementary dna microarray. / Choe, Jae-Gol; Kim, Yu Ri; Kim, Ki Nam; Choo, Hyo Jung; Shin, Jae Hoon; Lee, Yong Jin; Chung, June Key; Kim, Meyoung-Kon.
In: Nuclear Medicine Communications, Vol. 26, No. 12, 2005, p. 1155-1162.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Altered gene expression profiles by sodium/iodide symporter gene transfection in a human anaplastic thyroid carcinoma cell line using a radioactive complementary dna microarray
AU - Choe, Jae-Gol
AU - Kim, Yu Ri
AU - Kim, Ki Nam
AU - Choo, Hyo Jung
AU - Shin, Jae Hoon
AU - Lee, Yong Jin
AU - Chung, June Key
AU - Kim, Meyoung-Kon
PY - 2005
Y1 - 2005
N2 - The sodium/iodide symporter (NIS) is a membrane glycoprotein that mediates active I uptake during the treatment of cancer of the thyroid gland and extrathyroidal tissues. NIS gene transfection, a gene-therapy modality, has been introduced in many types of cancer, such as prostate cancer and breast cancer, and has demonstrated a high potential for the treatment of non-thyroidal cancers. To investigate the pattern of NIS gene expression and provide evidence of its beneficial effects in human anaplastic cancer ARO cells by using a radioactive complementary DNA (cDNA) microarray.
AB - The sodium/iodide symporter (NIS) is a membrane glycoprotein that mediates active I uptake during the treatment of cancer of the thyroid gland and extrathyroidal tissues. NIS gene transfection, a gene-therapy modality, has been introduced in many types of cancer, such as prostate cancer and breast cancer, and has demonstrated a high potential for the treatment of non-thyroidal cancers. To investigate the pattern of NIS gene expression and provide evidence of its beneficial effects in human anaplastic cancer ARO cells by using a radioactive complementary DNA (cDNA) microarray.
KW - CDNA microarray
KW - Human anaplastic cancer ARO cells
KW - PTP family
KW - Ras oncogene family
KW - Sodium/iodide symporter (NIS)
UR - http://www.scopus.com/inward/record.url?scp=27944440173&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=27944440173&partnerID=8YFLogxK
M3 - Article
C2 - 16264365
AN - SCOPUS:27944440173
VL - 26
SP - 1155
EP - 1162
JO - Nuclear Medicine Communications
JF - Nuclear Medicine Communications
SN - 0143-3636
IS - 12
ER -