Ameliorating effects of a nopal (Opuntia ficus-indica) complex on blood glucose in db/db mice

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This study investigated the effects of a nopal (Opuntia ficus-indica) complex (OF) on blood glucose metabolism in db/db mice for 4 weeks. Food and water intake significantly decreased in OF-treated mice compared to controls (p<0.05). In addition, blood glucose and plasma insulin levels were significantly reduced in the OF-treated group compared to the controls (p<0.05). Histopathological analysis showed that the morphology of pancreatic islets was improved in the OF-treated db/db mice. Immunohistochemistry of the pancreatic islets showed that insulin production and the number of β-cells apparently increased.

Original languageEnglish
Pages (from-to)255-259
Number of pages5
JournalFood Science and Biotechnology
Issue number1
Publication statusPublished - 2011 Jul 4



  • db/db mice
  • Hypoglycemic
  • Insulin
  • Opuntia ficus-indica
  • Pancreatic islet

ASJC Scopus subject areas

  • Food Science
  • Biotechnology
  • Applied Microbiology and Biotechnology

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