Ameliorating effects of a nopal (Opuntia ficus-indica) complex on blood glucose in db/db mice

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

This study investigated the effects of a nopal (Opuntia ficus-indica) complex (OF) on blood glucose metabolism in db/db mice for 4 weeks. Food and water intake significantly decreased in OF-treated mice compared to controls (p<0.05). In addition, blood glucose and plasma insulin levels were significantly reduced in the OF-treated group compared to the controls (p<0.05). Histopathological analysis showed that the morphology of pancreatic islets was improved in the OF-treated db/db mice. Immunohistochemistry of the pancreatic islets showed that insulin production and the number of β-cells apparently increased.

Original languageEnglish
Pages (from-to)255-259
Number of pages5
JournalFood Science and Biotechnology
Volume20
Issue number1
DOIs
Publication statusPublished - 2011 Jul 4

Fingerprint

Opuntia
Opuntia ficus-indica
blood glucose
Blood Glucose
islets of Langerhans
Islets of Langerhans
mice
insulin
Insulin
blood plasma
Drinking
immunohistochemistry
Cell Count
Eating
Immunohistochemistry
metabolism
water
cells

Keywords

  • db/db mice
  • Hypoglycemic
  • Insulin
  • Opuntia ficus-indica
  • Pancreatic islet

ASJC Scopus subject areas

  • Food Science
  • Biotechnology
  • Applied Microbiology and Biotechnology

Cite this

Ameliorating effects of a nopal (Opuntia ficus-indica) complex on blood glucose in db/db mice. / Son, Yong-Suk; Yoon, Jin A.; Lee, Sung-Joon; Kim, Han Kyeom.

In: Food Science and Biotechnology, Vol. 20, No. 1, 04.07.2011, p. 255-259.

Research output: Contribution to journalArticle

@article{215c2ea2e2954decb332a822b6371458,
title = "Ameliorating effects of a nopal (Opuntia ficus-indica) complex on blood glucose in db/db mice",
abstract = "This study investigated the effects of a nopal (Opuntia ficus-indica) complex (OF) on blood glucose metabolism in db/db mice for 4 weeks. Food and water intake significantly decreased in OF-treated mice compared to controls (p<0.05). In addition, blood glucose and plasma insulin levels were significantly reduced in the OF-treated group compared to the controls (p<0.05). Histopathological analysis showed that the morphology of pancreatic islets was improved in the OF-treated db/db mice. Immunohistochemistry of the pancreatic islets showed that insulin production and the number of β-cells apparently increased.",
keywords = "db/db mice, Hypoglycemic, Insulin, Opuntia ficus-indica, Pancreatic islet",
author = "Yong-Suk Son and Yoon, {Jin A.} and Sung-Joon Lee and Kim, {Han Kyeom}",
year = "2011",
month = "7",
day = "4",
doi = "10.1007/s10068-011-0035-4",
language = "English",
volume = "20",
pages = "255--259",
journal = "Food Science and Biotechnology",
issn = "1226-7708",
publisher = "Springer Netherlands",
number = "1",

}

TY - JOUR

T1 - Ameliorating effects of a nopal (Opuntia ficus-indica) complex on blood glucose in db/db mice

AU - Son, Yong-Suk

AU - Yoon, Jin A.

AU - Lee, Sung-Joon

AU - Kim, Han Kyeom

PY - 2011/7/4

Y1 - 2011/7/4

N2 - This study investigated the effects of a nopal (Opuntia ficus-indica) complex (OF) on blood glucose metabolism in db/db mice for 4 weeks. Food and water intake significantly decreased in OF-treated mice compared to controls (p<0.05). In addition, blood glucose and plasma insulin levels were significantly reduced in the OF-treated group compared to the controls (p<0.05). Histopathological analysis showed that the morphology of pancreatic islets was improved in the OF-treated db/db mice. Immunohistochemistry of the pancreatic islets showed that insulin production and the number of β-cells apparently increased.

AB - This study investigated the effects of a nopal (Opuntia ficus-indica) complex (OF) on blood glucose metabolism in db/db mice for 4 weeks. Food and water intake significantly decreased in OF-treated mice compared to controls (p<0.05). In addition, blood glucose and plasma insulin levels were significantly reduced in the OF-treated group compared to the controls (p<0.05). Histopathological analysis showed that the morphology of pancreatic islets was improved in the OF-treated db/db mice. Immunohistochemistry of the pancreatic islets showed that insulin production and the number of β-cells apparently increased.

KW - db/db mice

KW - Hypoglycemic

KW - Insulin

KW - Opuntia ficus-indica

KW - Pancreatic islet

UR - http://www.scopus.com/inward/record.url?scp=79959687742&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79959687742&partnerID=8YFLogxK

U2 - 10.1007/s10068-011-0035-4

DO - 10.1007/s10068-011-0035-4

M3 - Article

AN - SCOPUS:79959687742

VL - 20

SP - 255

EP - 259

JO - Food Science and Biotechnology

JF - Food Science and Biotechnology

SN - 1226-7708

IS - 1

ER -