Aminoindanol-based chiral derivatizing agents for the determination of the absolute configuration of carboxylic acids

Minjung Park, Seon Mi Kim, Kihang Choi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

New chiral derivatizing agents have been prepared through a simple, short-step synthesis. The absolute configuration of α-chiral carboxylic acids can be assigned on the basis of the NMR chemical shift difference between diastereomeric esters. Because of the modular structures of the agents, the anisotropic effect could be easily manipulated to afford large chemical shift differences even in polar solvents.

Original languageEnglish
Pages (from-to)8051-8054
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume10
Issue number40
DOIs
Publication statusPublished - 2012 Oct 28

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Chemical shift
Carboxylic Acids
carboxylic acids
chemical equilibrium
Esters
configurations
esters
Nuclear magnetic resonance
nuclear magnetic resonance
synthesis
aminoindanol

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Biochemistry

Cite this

Aminoindanol-based chiral derivatizing agents for the determination of the absolute configuration of carboxylic acids. / Park, Minjung; Kim, Seon Mi; Choi, Kihang.

In: Organic and Biomolecular Chemistry, Vol. 10, No. 40, 28.10.2012, p. 8051-8054.

Research output: Contribution to journalArticle

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