An adaptive-focus statistical shape model for segmentation and shape modeling of 3-D brain structures

Dinggang Shen, Edward H. Herskovits, Christos Davatzikos

Research output: Contribution to journalArticle

143 Citations (Scopus)

Abstract

This paper presents a deformable model for automatically segmenting brain structures from volumetric magnetic resonance (MR) images and obtaining point correspondences, using geometric and statistical information in a hierarchical scheme. Geometric information is embedded into the model via a set of affine-invariant attribute vectors, each of which characterizes the geometric structure around a point of the model from a local to a global scale. The attribute vectors, in conjunction with the deformation mechanism of the model, warranty that the model not only deforms to nearby edges, as is customary in most deformable surface models, but also that it determines point correspondences based on geometric similarity at different scales. The proposed model is adaptive in that it initially focuses on the most reliable structures of interest, and gradually shifts focus to other structures as those become closer to their respective targets and, therefore, more reliable. The proposed techniques have been used to segment boundaries of the ventricles, the caudate nucleus, and the lenticular nucleus from volumetric MR images.

Original languageEnglish
Pages (from-to)257-270
Number of pages14
JournalIEEE Transactions on Medical Imaging
Volume20
Issue number4
DOIs
Publication statusPublished - 2001 Apr 1
Externally publishedYes

Fingerprint

Statistical Models
Brain
Magnetic Resonance Spectroscopy
Corpus Striatum
Caudate Nucleus
Magnetic resonance

Keywords

  • Active contour
  • Adaptive focus model
  • Attribute vectors
  • Brain image segmentation
  • Deformable model
  • Deformable registration
  • Snake
  • Statistical shape model

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Electrical and Electronic Engineering
  • Computer Science Applications
  • Computational Theory and Mathematics

Cite this

An adaptive-focus statistical shape model for segmentation and shape modeling of 3-D brain structures. / Shen, Dinggang; Herskovits, Edward H.; Davatzikos, Christos.

In: IEEE Transactions on Medical Imaging, Vol. 20, No. 4, 01.04.2001, p. 257-270.

Research output: Contribution to journalArticle

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