An easily integrative and efficient micromixer and its application to the spectroscopic detection of glucose-catalyst reactions

D. J. Kim, H. J. Oh, T. H. Park, J. B. Choo, Sang Hoon Lee

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

The focus of this paper is on the fabrication of a PDMS-based passive efficient micromixer to be easily integrated into the other on-chip microfluidic system. The mixing is achieved by "strong stretching and folding," which employs a three-dimensional microchannel structure. By the simultaneously vertical and transversal dispersion of fluids, strong advection is developed. Owing to this powerful mixing performance (more than 70% of the mixing is accomplished within 2.3 mm over a wide range of Reynold number (Re)), the smaller integrative mixer can be realized. The feasibility and the potential usefulness of an integrative micromixer were evaluated by incorporating two mixers into the microchannel for the spectroscopic detection of a glucose-catalyst reaction. The results demonstrate a promising performance for diverse applications in the assay or synthesis of biological or chemical materials.

Original languageEnglish
Pages (from-to)293-298
Number of pages6
JournalAnalyst
Volume130
Issue number3
DOIs
Publication statusPublished - 2005 Mar 1
Externally publishedYes

Fingerprint

Microfluidics
Glucose
glucose
catalyst
Microchannels
Catalysts
Advection
Reynolds number
Stretching
folding
Assays
advection
assay
Fabrication
Fluids
fluid
detection

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

An easily integrative and efficient micromixer and its application to the spectroscopic detection of glucose-catalyst reactions. / Kim, D. J.; Oh, H. J.; Park, T. H.; Choo, J. B.; Lee, Sang Hoon.

In: Analyst, Vol. 130, No. 3, 01.03.2005, p. 293-298.

Research output: Contribution to journalArticle

@article{f3ec6bf03fae45d498a7300f00bc58cd,
title = "An easily integrative and efficient micromixer and its application to the spectroscopic detection of glucose-catalyst reactions",
abstract = "The focus of this paper is on the fabrication of a PDMS-based passive efficient micromixer to be easily integrated into the other on-chip microfluidic system. The mixing is achieved by {"}strong stretching and folding,{"} which employs a three-dimensional microchannel structure. By the simultaneously vertical and transversal dispersion of fluids, strong advection is developed. Owing to this powerful mixing performance (more than 70{\%} of the mixing is accomplished within 2.3 mm over a wide range of Reynold number (Re)), the smaller integrative mixer can be realized. The feasibility and the potential usefulness of an integrative micromixer were evaluated by incorporating two mixers into the microchannel for the spectroscopic detection of a glucose-catalyst reaction. The results demonstrate a promising performance for diverse applications in the assay or synthesis of biological or chemical materials.",
author = "Kim, {D. J.} and Oh, {H. J.} and Park, {T. H.} and Choo, {J. B.} and Lee, {Sang Hoon}",
year = "2005",
month = "3",
day = "1",
doi = "10.1039/b414180f",
language = "English",
volume = "130",
pages = "293--298",
journal = "The Analyst",
issn = "0003-2654",
publisher = "Royal Society of Chemistry",
number = "3",

}

TY - JOUR

T1 - An easily integrative and efficient micromixer and its application to the spectroscopic detection of glucose-catalyst reactions

AU - Kim, D. J.

AU - Oh, H. J.

AU - Park, T. H.

AU - Choo, J. B.

AU - Lee, Sang Hoon

PY - 2005/3/1

Y1 - 2005/3/1

N2 - The focus of this paper is on the fabrication of a PDMS-based passive efficient micromixer to be easily integrated into the other on-chip microfluidic system. The mixing is achieved by "strong stretching and folding," which employs a three-dimensional microchannel structure. By the simultaneously vertical and transversal dispersion of fluids, strong advection is developed. Owing to this powerful mixing performance (more than 70% of the mixing is accomplished within 2.3 mm over a wide range of Reynold number (Re)), the smaller integrative mixer can be realized. The feasibility and the potential usefulness of an integrative micromixer were evaluated by incorporating two mixers into the microchannel for the spectroscopic detection of a glucose-catalyst reaction. The results demonstrate a promising performance for diverse applications in the assay or synthesis of biological or chemical materials.

AB - The focus of this paper is on the fabrication of a PDMS-based passive efficient micromixer to be easily integrated into the other on-chip microfluidic system. The mixing is achieved by "strong stretching and folding," which employs a three-dimensional microchannel structure. By the simultaneously vertical and transversal dispersion of fluids, strong advection is developed. Owing to this powerful mixing performance (more than 70% of the mixing is accomplished within 2.3 mm over a wide range of Reynold number (Re)), the smaller integrative mixer can be realized. The feasibility and the potential usefulness of an integrative micromixer were evaluated by incorporating two mixers into the microchannel for the spectroscopic detection of a glucose-catalyst reaction. The results demonstrate a promising performance for diverse applications in the assay or synthesis of biological or chemical materials.

UR - http://www.scopus.com/inward/record.url?scp=15244341658&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=15244341658&partnerID=8YFLogxK

U2 - 10.1039/b414180f

DO - 10.1039/b414180f

M3 - Article

C2 - 15724156

AN - SCOPUS:15244341658

VL - 130

SP - 293

EP - 298

JO - The Analyst

JF - The Analyst

SN - 0003-2654

IS - 3

ER -