An easily integrative and efficient micromixer and its application to the spectroscopic detection of glucose-catalyst reactions

D. J. Kim, H. J. Oh, T. H. Park, J. B. Choo, Sang Hoon Lee

Research output: Contribution to journalArticle

46 Citations (Scopus)


The focus of this paper is on the fabrication of a PDMS-based passive efficient micromixer to be easily integrated into the other on-chip microfluidic system. The mixing is achieved by "strong stretching and folding," which employs a three-dimensional microchannel structure. By the simultaneously vertical and transversal dispersion of fluids, strong advection is developed. Owing to this powerful mixing performance (more than 70% of the mixing is accomplished within 2.3 mm over a wide range of Reynold number (Re)), the smaller integrative mixer can be realized. The feasibility and the potential usefulness of an integrative micromixer were evaluated by incorporating two mixers into the microchannel for the spectroscopic detection of a glucose-catalyst reaction. The results demonstrate a promising performance for diverse applications in the assay or synthesis of biological or chemical materials.

Original languageEnglish
Pages (from-to)293-298
Number of pages6
Issue number3
Publication statusPublished - 2005 Mar 1
Externally publishedYes


ASJC Scopus subject areas

  • Analytical Chemistry

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