An iminocoumarin-Cu(ii) ensemble-based chemodosimeter toward thiols

Hyo Sung Jung, Ji Hye Han, Yoichi Habata, Chulhun Kang, Jong Seung Kim

Research output: Contribution to journalArticle

143 Citations (Scopus)

Abstract

An ‘ensemble’-based fluoregenic chemodosimeter 1-Cu(ii) for detection of thiols is reported. Complex 1-Cu(ii) sensitively senses thiols followed by hydrolysis to give a marked fluorescence enhancement over other amino acids at pH 7.4 under aqueous media. Confocal microscopic imaging of complex 1-Cu(ii) is also herewith demonstrated for cellular thiol detection in HepG2 cells.

Original languageEnglish
Pages (from-to)5142-5144
Number of pages3
JournalChemical Communications
Volume47
Issue number18
DOIs
Publication statusPublished - 2011 Apr 19

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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