An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species

Chiew San Fang; Kyung Hwan Oh; Aram Oh; Kwangyeol Lee; Seonhwa Park; Sinyoung Kim; Jin Kyoon Park; Haesik Yang

doi:10.1039/c6cc00353b

An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species

Chiew San Fang, Kyung Hwan Oh, Aram Oh, Kwangyeol Lee, Seonhwa Park, Sinyoung Kim, Jin Kyoon Park, Haesik Yang

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

This communication reports a new nanocatalytic scheme based on the facts that the redox reaction between a highly outer-sphere-reaction-philic (OSR-philic) species and a highly inner-sphere-reaction-philic (ISR-philic) species is slow and that an OSR- and ISR-philic Au-nanocatalyst label can mediate the two different types of redox species. This scheme allows highly sensitive and incubation free detection of creatine kinase-MB.

Original language	English
Pages (from-to)	5884-5887
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	34
DOIs	https://doi.org/10.1039/c6cc00353b
Publication status	Published - 2016 Apr 30

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species. / Fang, Chiew San; Oh, Kyung Hwan; Oh, Aram et al.

In: Chemical Communications, Vol. 52, No. 34, 30.04.2016, p. 5884-5887.

Research output: Contribution to journal › Article › peer-review

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abstract = "This communication reports a new nanocatalytic scheme based on the facts that the redox reaction between a highly outer-sphere-reaction-philic (OSR-philic) species and a highly inner-sphere-reaction-philic (ISR-philic) species is slow and that an OSR- and ISR-philic Au-nanocatalyst label can mediate the two different types of redox species. This scheme allows highly sensitive and incubation free detection of creatine kinase-MB.",

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AU - Oh, Kyung Hwan

AU - Oh, Aram

AU - Lee, Kwangyeol

AU - Park, Seonhwa

AU - Kim, Sinyoung

AU - Park, Jin Kyoon

AU - Yang, Haesik

N1 - Funding Information: This work was supported by the National Research Foundation of Korea (2015R1A2A2A01002695, 2015M2A8A5021905, and 2012-M3C1A1-048862). Publisher Copyright: © The Royal Society of Chemistry 2016.

PY - 2016/4/30

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N2 - This communication reports a new nanocatalytic scheme based on the facts that the redox reaction between a highly outer-sphere-reaction-philic (OSR-philic) species and a highly inner-sphere-reaction-philic (ISR-philic) species is slow and that an OSR- and ISR-philic Au-nanocatalyst label can mediate the two different types of redox species. This scheme allows highly sensitive and incubation free detection of creatine kinase-MB.

AB - This communication reports a new nanocatalytic scheme based on the facts that the redox reaction between a highly outer-sphere-reaction-philic (OSR-philic) species and a highly inner-sphere-reaction-philic (ISR-philic) species is slow and that an OSR- and ISR-philic Au-nanocatalyst label can mediate the two different types of redox species. This scheme allows highly sensitive and incubation free detection of creatine kinase-MB.

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An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species

Abstract

ASJC Scopus subject areas

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