Abstract
By rationally employing enzymes for signal amplification, an ultrasensitive aptasensor was developed and successfully tested in a system designed to detect lysozyme with a detection limit of 0.1 fM. This detection limit is nearly three orders of magnitude lower than those of any previously reported DNAzyme-based aptasensors.
| Original language | English |
|---|---|
| Pages (from-to) | 9876-9878 |
| Number of pages | 3 |
| Journal | Chemical Communications |
| Volume | 47 |
| Issue number | 35 |
| DOIs | |
| Publication status | Published - 2011 Sep 21 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry
Cite this
An ultrasensitive peroxidase DNAzyme-associated aptasensor that utilizes a target-triggered enzymatic signal amplification strategy. / Fu, Rongzhan; Jeon, Kyungeun; Jung, Cheulhee; Park, Hyun Gyu.
In: Chemical Communications, Vol. 47, No. 35, 21.09.2011, p. 9876-9878.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - An ultrasensitive peroxidase DNAzyme-associated aptasensor that utilizes a target-triggered enzymatic signal amplification strategy
AU - Fu, Rongzhan
AU - Jeon, Kyungeun
AU - Jung, Cheulhee
AU - Park, Hyun Gyu
PY - 2011/9/21
Y1 - 2011/9/21
N2 - By rationally employing enzymes for signal amplification, an ultrasensitive aptasensor was developed and successfully tested in a system designed to detect lysozyme with a detection limit of 0.1 fM. This detection limit is nearly three orders of magnitude lower than those of any previously reported DNAzyme-based aptasensors.
AB - By rationally employing enzymes for signal amplification, an ultrasensitive aptasensor was developed and successfully tested in a system designed to detect lysozyme with a detection limit of 0.1 fM. This detection limit is nearly three orders of magnitude lower than those of any previously reported DNAzyme-based aptasensors.
UR - http://www.scopus.com/inward/record.url?scp=80052098913&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052098913&partnerID=8YFLogxK
U2 - 10.1039/c1cc13122b
DO - 10.1039/c1cc13122b
M3 - Article
C2 - 21826311
AN - SCOPUS:80052098913
VL - 47
SP - 9876
EP - 9878
JO - Chemical Communications
JF - Chemical Communications
SN - 1359-7345
IS - 35
ER -