Analyses of vessel densities and foveal avascular zones using four optical coherence tomography angiography devices

Seo Yeon Park, Ki Tae Nam, Cheolmin Yun, Sungmin Jang

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To compare the vessel density (VD) and foveal avascular zone (FAZ) area using four different optical coherence tomography angiography (OCTA) images. Methods: This prospective study analyzed the OCTA images of consecutive healthy subjects using Plex-Elite (Carl Zeiss), DRI OCT-1 Atlantis (Topcon), AngioPlex (Carl Zeiss), and Spectralis OCTA (Heidelberg Engineering). The VD and FAZ areas were calculated using the OCTA images with a 3 x 3 mm2 volume scan pattern centered on the fovea. Results: The VD (%) of the superficial capillary plexus (SCP) and deep capillary plexus (DCP) were different using the four devices: Plex-Elite (42.17 ± 2.79, 43.71 ± 2.36), DRI OCT-1 Atlantis (28.70 ± 2.87, 30.27 ± 3.02), AngioPlex (28.32 ± 6.68, 33.33 ± 5.44), and Spectralis OCTA (27.86 ± 4.13, 28.54 ± 3.14), respectively; p < 0.001). The FAZ area (mm2) of the SCP and DCP were different using the four devices: Plex-Elite (0.276 ± 0.097, 0.340 ± 0.100), DRI OCT-1 Atlantis (0.281 ± 0.102, 0.354 ± 0.119), AngioPlex (0.269 ± 0.099, 0.422 ± 0.120), and Spectralis OCTA (0.272 ± 0.079, 0.298 ± 0.106), respectively; p < 0.001). The VD of the SCP and DCP had no significant correlation using the four devices (all, p > 0.05), but the FAZ area had positive correlations using the four devices (all, p < 0.001). Conclusions: The four OCTA devices provided different VD and FAZ areas, so these differences should be considered in analyzing OCTA images.

Original languageEnglish
Pages (from-to)482-490
Number of pages9
JournalJournal of Korean Ophthalmological Society
Volume61
Issue number5
DOIs
Publication statusPublished - 2020 May

Keywords

  • Foveal avascular zone
  • Optical coherence tomography angiography
  • Vessel density

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint Dive into the research topics of 'Analyses of vessel densities and foveal avascular zones using four optical coherence tomography angiography devices'. Together they form a unique fingerprint.

Cite this