Abstract
Patients with Parkinson's disease (PD) suffer from an increased resistance to passive movement of a joint, called as rigidity. Stretch reflex and shortening reaction were suggested to be associated to the rigidity, however, the mechanism is still poorly understood. We hypothesized that the co-contraction of antagonistic muscle pairs is enhanced in patients with PD and this induces resistance persisting throughout its range of motion. To test the hypothesis, we developed a motorized device for application of passive movement of the wrist joint and investigated the co-contraction of muscles during passive movement. It consisted of a servo motor connected to a rotating axis with a timing belt, load cell for the measurement of resistance, and other elements for the fixation of arm and hand. Repetitive passive movement was applied to the wrist joint of patients. Cocontraction of antagonistic muscle pairs was significantly greater in patients than in normal subjects (p<0.001), suggesting that the enhanced co-contraction is associated with the mechanical resistance during passive movement, i.e. rigidity. Cocontraction during extended state was greater than the other states (p<0.001), which implies that the length-feedback mechanism may play the important role in co-contraction.
| Original language | English |
|---|---|
| Pages (from-to) | 2291-2297 |
| Number of pages | 7 |
| Journal | Bio-Medical Materials and Engineering |
| Volume | 24 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2014 Jan 1 |
Fingerprint
Keywords
- Co-contraction
- Motorized device
- Parkinson's disease
- Passive movement
- Rigidity
ASJC Scopus subject areas
- Biomaterials
- Biomedical Engineering
Cite this
Analysis of antagonistic co-contractions with motorized passive movement device in patients with parkinson's disease. / Kwon, Yuri; Kim, Ji Won; Ho, Yeji; Jeon, Hyeong Min; Bang, Min Jung; Eom, Gwang Moon; Koh, Seong Beom.
In: Bio-Medical Materials and Engineering, Vol. 24, No. 6, 01.01.2014, p. 2291-2297.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Analysis of antagonistic co-contractions with motorized passive movement device in patients with parkinson's disease
AU - Kwon, Yuri
AU - Kim, Ji Won
AU - Ho, Yeji
AU - Jeon, Hyeong Min
AU - Bang, Min Jung
AU - Eom, Gwang Moon
AU - Koh, Seong Beom
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Patients with Parkinson's disease (PD) suffer from an increased resistance to passive movement of a joint, called as rigidity. Stretch reflex and shortening reaction were suggested to be associated to the rigidity, however, the mechanism is still poorly understood. We hypothesized that the co-contraction of antagonistic muscle pairs is enhanced in patients with PD and this induces resistance persisting throughout its range of motion. To test the hypothesis, we developed a motorized device for application of passive movement of the wrist joint and investigated the co-contraction of muscles during passive movement. It consisted of a servo motor connected to a rotating axis with a timing belt, load cell for the measurement of resistance, and other elements for the fixation of arm and hand. Repetitive passive movement was applied to the wrist joint of patients. Cocontraction of antagonistic muscle pairs was significantly greater in patients than in normal subjects (p<0.001), suggesting that the enhanced co-contraction is associated with the mechanical resistance during passive movement, i.e. rigidity. Cocontraction during extended state was greater than the other states (p<0.001), which implies that the length-feedback mechanism may play the important role in co-contraction.
AB - Patients with Parkinson's disease (PD) suffer from an increased resistance to passive movement of a joint, called as rigidity. Stretch reflex and shortening reaction were suggested to be associated to the rigidity, however, the mechanism is still poorly understood. We hypothesized that the co-contraction of antagonistic muscle pairs is enhanced in patients with PD and this induces resistance persisting throughout its range of motion. To test the hypothesis, we developed a motorized device for application of passive movement of the wrist joint and investigated the co-contraction of muscles during passive movement. It consisted of a servo motor connected to a rotating axis with a timing belt, load cell for the measurement of resistance, and other elements for the fixation of arm and hand. Repetitive passive movement was applied to the wrist joint of patients. Cocontraction of antagonistic muscle pairs was significantly greater in patients than in normal subjects (p<0.001), suggesting that the enhanced co-contraction is associated with the mechanical resistance during passive movement, i.e. rigidity. Cocontraction during extended state was greater than the other states (p<0.001), which implies that the length-feedback mechanism may play the important role in co-contraction.
KW - Co-contraction
KW - Motorized device
KW - Parkinson's disease
KW - Passive movement
KW - Rigidity
UR - http://www.scopus.com/inward/record.url?scp=84907259416&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84907259416&partnerID=8YFLogxK
U2 - 10.3233/BME-141042
DO - 10.3233/BME-141042
M3 - Article
C2 - 25226929
AN - SCOPUS:84907259416
VL - 24
SP - 2291
EP - 2297
JO - Bio-Medical Materials and Engineering
JF - Bio-Medical Materials and Engineering
SN - 0959-2989
IS - 6
ER -