Analysis of antagonistic co-contractions with motorized passive movement device in patients with parkinson's disease

Yuri Kwon, Ji Won Kim, Yeji Ho, Hyeong Min Jeon, Min Jung Bang, Gwang Moon Eom, Seong Beom Koh

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Patients with Parkinson's disease (PD) suffer from an increased resistance to passive movement of a joint, called as rigidity. Stretch reflex and shortening reaction were suggested to be associated to the rigidity, however, the mechanism is still poorly understood. We hypothesized that the co-contraction of antagonistic muscle pairs is enhanced in patients with PD and this induces resistance persisting throughout its range of motion. To test the hypothesis, we developed a motorized device for application of passive movement of the wrist joint and investigated the co-contraction of muscles during passive movement. It consisted of a servo motor connected to a rotating axis with a timing belt, load cell for the measurement of resistance, and other elements for the fixation of arm and hand. Repetitive passive movement was applied to the wrist joint of patients. Cocontraction of antagonistic muscle pairs was significantly greater in patients than in normal subjects (p<0.001), suggesting that the enhanced co-contraction is associated with the mechanical resistance during passive movement, i.e. rigidity. Cocontraction during extended state was greater than the other states (p<0.001), which implies that the length-feedback mechanism may play the important role in co-contraction.

Original languageEnglish
Pages (from-to)2291-2297
Number of pages7
JournalBio-Medical Materials and Engineering
Volume24
Issue number6
DOIs
Publication statusPublished - 2014 Jan 1

Keywords

  • Co-contraction
  • Motorized device
  • Parkinson's disease
  • Passive movement
  • Rigidity

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering

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