Analysis of bacterial biofilms on a cochlear implant following methicillin-resistant Staphylococcus aureus infection

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5 Citations (Scopus)

Abstract

To demonstrate biofilm formations on a cochlear implant magnet of a pediatric patient suffering from a methicillin-resistant Staphylococcus aureus (MRSA) infection. The appearance of biofilm colonies was analyzed on different magnet sections. The appearance of MRSA biofilms on the surface of an explanted cochlear implant was analyzed by scanning electron microscopy (SEM), focusing on the pattern of extracellular polymeric substances (EPS) within the biofilms. SEM revealed unique biofilms with a three-dimensional EPS complex and tower-like formations. Biofilm configurations changed from the margin to the center of the magnet. Biofilms were solitary and scattered at the margin; large and plate-like in the center; and stacked in layers, forming towers and water channels, in the middle region. After a MRSA infection, biofilm formations were observed on the surface of a magnet. Bacterial biofilms provide optimal conditions for bacterial growth and antibiotic resistance and can cause intractable infections that lead to device failure.

Original languageEnglish
Pages (from-to)172-177
Number of pages6
JournalKorean Journal of Audiology
Volume19
Issue number3
DOIs
Publication statusPublished - 2015 Jan 1

Fingerprint

Cochlear Implants
Methicillin-Resistant Staphylococcus aureus
Biofilms
Magnets
Infection
Electron Scanning Microscopy
Bacterial Drug Resistance
Equipment Failure
Aquaporins
Pediatrics

Keywords

  • Biofilm
  • Cochlear implant
  • Extracellular polymeric substance
  • Methicillin-resistant Staphylococcus aureus
  • Scanning electron microscopy

ASJC Scopus subject areas

  • Sensory Systems
  • Speech and Hearing

Cite this

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abstract = "To demonstrate biofilm formations on a cochlear implant magnet of a pediatric patient suffering from a methicillin-resistant Staphylococcus aureus (MRSA) infection. The appearance of biofilm colonies was analyzed on different magnet sections. The appearance of MRSA biofilms on the surface of an explanted cochlear implant was analyzed by scanning electron microscopy (SEM), focusing on the pattern of extracellular polymeric substances (EPS) within the biofilms. SEM revealed unique biofilms with a three-dimensional EPS complex and tower-like formations. Biofilm configurations changed from the margin to the center of the magnet. Biofilms were solitary and scattered at the margin; large and plate-like in the center; and stacked in layers, forming towers and water channels, in the middle region. After a MRSA infection, biofilm formations were observed on the surface of a magnet. Bacterial biofilms provide optimal conditions for bacterial growth and antibiotic resistance and can cause intractable infections that lead to device failure.",
keywords = "Biofilm, Cochlear implant, Extracellular polymeric substance, Methicillin-resistant Staphylococcus aureus, Scanning electron microscopy",
author = "Im, {Gi Jung} and An, {Yun Suk} and June Choi and Jae-Jun Song and Sungwon Chae and Jung, {Hak Hyun}",
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AU - Im, Gi Jung

AU - An, Yun Suk

AU - Choi, June

AU - Song, Jae-Jun

AU - Chae, Sungwon

AU - Jung, Hak Hyun

PY - 2015/1/1

Y1 - 2015/1/1

N2 - To demonstrate biofilm formations on a cochlear implant magnet of a pediatric patient suffering from a methicillin-resistant Staphylococcus aureus (MRSA) infection. The appearance of biofilm colonies was analyzed on different magnet sections. The appearance of MRSA biofilms on the surface of an explanted cochlear implant was analyzed by scanning electron microscopy (SEM), focusing on the pattern of extracellular polymeric substances (EPS) within the biofilms. SEM revealed unique biofilms with a three-dimensional EPS complex and tower-like formations. Biofilm configurations changed from the margin to the center of the magnet. Biofilms were solitary and scattered at the margin; large and plate-like in the center; and stacked in layers, forming towers and water channels, in the middle region. After a MRSA infection, biofilm formations were observed on the surface of a magnet. Bacterial biofilms provide optimal conditions for bacterial growth and antibiotic resistance and can cause intractable infections that lead to device failure.

AB - To demonstrate biofilm formations on a cochlear implant magnet of a pediatric patient suffering from a methicillin-resistant Staphylococcus aureus (MRSA) infection. The appearance of biofilm colonies was analyzed on different magnet sections. The appearance of MRSA biofilms on the surface of an explanted cochlear implant was analyzed by scanning electron microscopy (SEM), focusing on the pattern of extracellular polymeric substances (EPS) within the biofilms. SEM revealed unique biofilms with a three-dimensional EPS complex and tower-like formations. Biofilm configurations changed from the margin to the center of the magnet. Biofilms were solitary and scattered at the margin; large and plate-like in the center; and stacked in layers, forming towers and water channels, in the middle region. After a MRSA infection, biofilm formations were observed on the surface of a magnet. Bacterial biofilms provide optimal conditions for bacterial growth and antibiotic resistance and can cause intractable infections that lead to device failure.

KW - Biofilm

KW - Cochlear implant

KW - Extracellular polymeric substance

KW - Methicillin-resistant Staphylococcus aureus

KW - Scanning electron microscopy

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