Analysis of dural sac thickness in the human cervical spine

Soonwook Kwon, Seung-Woo Suh, Dasom Kim, Im Joo Rhyu, Hyunung Yu, Seung Woo Han, Jae-Young Hong

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

The thickness of the dura mater in the human cervical spine can vary between individuals and by vertebral level; these differences can result in various clinical outcomes. The purpose was to measure and analyze cervical dura mater thickness. Microscopic measurements were made of tissue from human cadavers. The subjects were nine human cadavers with no previous history of spinal deformity or surgery. Fourteen segments of both anterior and posterior dura mater from the C1 to C7 cervical vertebrae were obtained. Dura mater thickness was measured using an infrared laser-based confocal microscope. Statistical analyses were performed to examine the relationships of cervical dura mater thickness with vertebral level, age, and sex. The overall average cervical dura mater thickness was 379.3 × 10−3 mm. Statistically significant differences in thickness were found between the anterior and posterior segments (P < 0.0001). Moreover, the thickness at each vertebral level was significantly different from the thicknesses at the other levels (P < 0.05). The posterior dura mater thickness was highest at C1 and lowest at C5/6. Posterior dura mater thickness was significantly different at the axial, sub-axial, and lower cervical levels, whereas anterior dura mater thickness was relatively constant among levels. A significant correlation was found between thickness and age (P < 0.05); however, the average dura mater thickness was not significantly different between males and females. This study shows anatomical differences in cervical dura mater thickness with respect to vertebral level and age. These results provide anatomical information that will inform basic research and clinical approaches.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalAnatomical Science International
DOIs
Publication statusAccepted/In press - 2017 Aug 2

Keywords

  • Cadaver
  • Cervical spine
  • Confocal microscopy
  • Dura mater
  • Thickness

ASJC Scopus subject areas

  • Anatomy

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