Analysis of familial factors using the basic and specific (BASP) classification in Korean patients with androgenetic alopecia

Won Soo Lee, Yoonseok Oh, Jae Hong Ji, Jang Kyu Park, Do Won Kim, Woo Young Sim, Hyung Ok Kim, Seon Wook Hwang, Tae Young Yoon, Young Chul Kye, Gwang Seong Choi, Moon Bum Kim, Chang Hoon Huh, Byung In Ro, Seong Jin Kim, Jae Hong Kim, Yoonhee Lee

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Background: The mechanisms and inheritance of androgenetic alopecia (AGA) have yet to be elucidated. Several clinical studies suggest that a predisposition to AGA is affected by a variety of paternal and/or maternal hereditary factors. No previous study has addressed the association of AGA with family history based on the pattern of hair loss. Objectives: The purpose of this study was to investigate paternal and/or maternal genetic influences in each type of hair loss pattern using the basic and specific (BASP) classification and to explore whether the morphology of AGA tends to be inherited in family members. Methods: Between October 2007 and September 2008, 1220 Korean participants, 998 male and 222 female, were classified according to the BASP classification at 13 university dermatologic centers. Information was collected using a standard questionnaire and BASP classification sheet. Results: Parental influences on anterior hairline shape in men were predominantly from the paternal side, whereas these effects were less notable in women. In the absence of a family history, statistical analysis showed a higher frequency for early-onset AGA than late-onset AGA (Pearson χ2 P < .05). Basic types of hair loss had a higher degree of inheritance from the paternal side of the family, regardless of specific type. Limitations: The evaluation of hair loss pattern and family history was done by the patients. Conclusions: Familial factors affecting the morphology of AGA differ between male and female individuals, and for each type of BASP classification.

Original languageEnglish
Pages (from-to)40-47
Number of pages8
JournalJournal of the American Academy of Dermatology
Volume65
Issue number1
DOIs
Publication statusPublished - 2011 Jul 1

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Alopecia
Statistical Factor Analysis
Mothers

Keywords

  • androgenetic alopecia
  • basic and specific classification
  • family history

ASJC Scopus subject areas

  • Dermatology

Cite this

Analysis of familial factors using the basic and specific (BASP) classification in Korean patients with androgenetic alopecia. / Lee, Won Soo; Oh, Yoonseok; Ji, Jae Hong; Park, Jang Kyu; Kim, Do Won; Sim, Woo Young; Kim, Hyung Ok; Hwang, Seon Wook; Yoon, Tae Young; Kye, Young Chul; Choi, Gwang Seong; Kim, Moon Bum; Huh, Chang Hoon; Ro, Byung In; Kim, Seong Jin; Kim, Jae Hong; Lee, Yoonhee.

In: Journal of the American Academy of Dermatology, Vol. 65, No. 1, 01.07.2011, p. 40-47.

Research output: Contribution to journalArticle

Lee, WS, Oh, Y, Ji, JH, Park, JK, Kim, DW, Sim, WY, Kim, HO, Hwang, SW, Yoon, TY, Kye, YC, Choi, GS, Kim, MB, Huh, CH, Ro, BI, Kim, SJ, Kim, JH & Lee, Y 2011, 'Analysis of familial factors using the basic and specific (BASP) classification in Korean patients with androgenetic alopecia', Journal of the American Academy of Dermatology, vol. 65, no. 1, pp. 40-47. https://doi.org/10.1016/j.jaad.2010.05.005
Lee, Won Soo ; Oh, Yoonseok ; Ji, Jae Hong ; Park, Jang Kyu ; Kim, Do Won ; Sim, Woo Young ; Kim, Hyung Ok ; Hwang, Seon Wook ; Yoon, Tae Young ; Kye, Young Chul ; Choi, Gwang Seong ; Kim, Moon Bum ; Huh, Chang Hoon ; Ro, Byung In ; Kim, Seong Jin ; Kim, Jae Hong ; Lee, Yoonhee. / Analysis of familial factors using the basic and specific (BASP) classification in Korean patients with androgenetic alopecia. In: Journal of the American Academy of Dermatology. 2011 ; Vol. 65, No. 1. pp. 40-47.
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abstract = "Background: The mechanisms and inheritance of androgenetic alopecia (AGA) have yet to be elucidated. Several clinical studies suggest that a predisposition to AGA is affected by a variety of paternal and/or maternal hereditary factors. No previous study has addressed the association of AGA with family history based on the pattern of hair loss. Objectives: The purpose of this study was to investigate paternal and/or maternal genetic influences in each type of hair loss pattern using the basic and specific (BASP) classification and to explore whether the morphology of AGA tends to be inherited in family members. Methods: Between October 2007 and September 2008, 1220 Korean participants, 998 male and 222 female, were classified according to the BASP classification at 13 university dermatologic centers. Information was collected using a standard questionnaire and BASP classification sheet. Results: Parental influences on anterior hairline shape in men were predominantly from the paternal side, whereas these effects were less notable in women. In the absence of a family history, statistical analysis showed a higher frequency for early-onset AGA than late-onset AGA (Pearson χ2 P < .05). Basic types of hair loss had a higher degree of inheritance from the paternal side of the family, regardless of specific type. Limitations: The evaluation of hair loss pattern and family history was done by the patients. Conclusions: Familial factors affecting the morphology of AGA differ between male and female individuals, and for each type of BASP classification.",
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AU - Lee, Won Soo

AU - Oh, Yoonseok

AU - Ji, Jae Hong

AU - Park, Jang Kyu

AU - Kim, Do Won

AU - Sim, Woo Young

AU - Kim, Hyung Ok

AU - Hwang, Seon Wook

AU - Yoon, Tae Young

AU - Kye, Young Chul

AU - Choi, Gwang Seong

AU - Kim, Moon Bum

AU - Huh, Chang Hoon

AU - Ro, Byung In

AU - Kim, Seong Jin

AU - Kim, Jae Hong

AU - Lee, Yoonhee

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N2 - Background: The mechanisms and inheritance of androgenetic alopecia (AGA) have yet to be elucidated. Several clinical studies suggest that a predisposition to AGA is affected by a variety of paternal and/or maternal hereditary factors. No previous study has addressed the association of AGA with family history based on the pattern of hair loss. Objectives: The purpose of this study was to investigate paternal and/or maternal genetic influences in each type of hair loss pattern using the basic and specific (BASP) classification and to explore whether the morphology of AGA tends to be inherited in family members. Methods: Between October 2007 and September 2008, 1220 Korean participants, 998 male and 222 female, were classified according to the BASP classification at 13 university dermatologic centers. Information was collected using a standard questionnaire and BASP classification sheet. Results: Parental influences on anterior hairline shape in men were predominantly from the paternal side, whereas these effects were less notable in women. In the absence of a family history, statistical analysis showed a higher frequency for early-onset AGA than late-onset AGA (Pearson χ2 P < .05). Basic types of hair loss had a higher degree of inheritance from the paternal side of the family, regardless of specific type. Limitations: The evaluation of hair loss pattern and family history was done by the patients. Conclusions: Familial factors affecting the morphology of AGA differ between male and female individuals, and for each type of BASP classification.

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