Analysis of human tissue management models for medical research

Preparation for implementation of the 2012 revision of the bioethics and safety act of Korea

Young Joon Ryu, Han Kyeom Kim, Sejin Jang, Young Mo Koo

Research output: Contribution to journalArticle

Abstract

Efficient management of human tissue samples is a critical issue; the supply of samples is unable to satisfy the current demands for research. Lack of informed consent is also an ethical problem. One of the goals of the 2012 revision of Korea's Bioethics and Safety Act was to implement regulations that govern the management of human tissue samples. To remain competitive, medical institutions must prepare for these future changes. In this report, we review two tissue management models that are currently in use; model 1 is the most common system utilized by hospitals in Korea and model 2 is implemented by some of the larger institutions. We also propose three alternative models that offer advantages over the systems currently in use. Model 3 is a multi-bank model that protects the independence of physicians and pathologists. Model 4 utilizes a comprehensive single bioresource bank; although in this case, the pathologists gain control of the samples, which may make it difficult to implement. Model 5, which employs a bioresource utilization steering committee (BUSC), is viable to implement and still maintains the advantages of Model 4. To comply with the upcoming law, we suggest that physicians and pathologists in an institution should collaborate to choose one of the improved models of tissue management system that best fits for their situation.

Original languageEnglish
Pages (from-to)803-807
Number of pages5
JournalJournal of Korean Medical Science
Volume28
Issue number6
DOIs
Publication statusPublished - 2013 Jun 1

Fingerprint

Bioethics
Korea
Biomedical Research
Safety
Physicians
Informed Consent
Research
Pathologists

Keywords

  • Bioethics and safety act
  • Bioresource bank
  • Ethics committees
  • Human tissue management model
  • Research

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Analysis of human tissue management models for medical research : Preparation for implementation of the 2012 revision of the bioethics and safety act of Korea. / Ryu, Young Joon; Kim, Han Kyeom; Jang, Sejin; Koo, Young Mo.

In: Journal of Korean Medical Science, Vol. 28, No. 6, 01.06.2013, p. 803-807.

Research output: Contribution to journalArticle

@article{1fa553a9ee254b31a616fcc9671dac78,
title = "Analysis of human tissue management models for medical research: Preparation for implementation of the 2012 revision of the bioethics and safety act of Korea",
abstract = "Efficient management of human tissue samples is a critical issue; the supply of samples is unable to satisfy the current demands for research. Lack of informed consent is also an ethical problem. One of the goals of the 2012 revision of Korea's Bioethics and Safety Act was to implement regulations that govern the management of human tissue samples. To remain competitive, medical institutions must prepare for these future changes. In this report, we review two tissue management models that are currently in use; model 1 is the most common system utilized by hospitals in Korea and model 2 is implemented by some of the larger institutions. We also propose three alternative models that offer advantages over the systems currently in use. Model 3 is a multi-bank model that protects the independence of physicians and pathologists. Model 4 utilizes a comprehensive single bioresource bank; although in this case, the pathologists gain control of the samples, which may make it difficult to implement. Model 5, which employs a bioresource utilization steering committee (BUSC), is viable to implement and still maintains the advantages of Model 4. To comply with the upcoming law, we suggest that physicians and pathologists in an institution should collaborate to choose one of the improved models of tissue management system that best fits for their situation.",
keywords = "Bioethics and safety act, Bioresource bank, Ethics committees, Human tissue management model, Research",
author = "Ryu, {Young Joon} and Kim, {Han Kyeom} and Sejin Jang and Koo, {Young Mo}",
year = "2013",
month = "6",
day = "1",
doi = "10.3346/ jkms.2013.28.6.803",
language = "English",
volume = "28",
pages = "803--807",
journal = "Journal of Korean Medical Science",
issn = "1011-8934",
publisher = "Korean Academy of Medical Science",
number = "6",

}

TY - JOUR

T1 - Analysis of human tissue management models for medical research

T2 - Preparation for implementation of the 2012 revision of the bioethics and safety act of Korea

AU - Ryu, Young Joon

AU - Kim, Han Kyeom

AU - Jang, Sejin

AU - Koo, Young Mo

PY - 2013/6/1

Y1 - 2013/6/1

N2 - Efficient management of human tissue samples is a critical issue; the supply of samples is unable to satisfy the current demands for research. Lack of informed consent is also an ethical problem. One of the goals of the 2012 revision of Korea's Bioethics and Safety Act was to implement regulations that govern the management of human tissue samples. To remain competitive, medical institutions must prepare for these future changes. In this report, we review two tissue management models that are currently in use; model 1 is the most common system utilized by hospitals in Korea and model 2 is implemented by some of the larger institutions. We also propose three alternative models that offer advantages over the systems currently in use. Model 3 is a multi-bank model that protects the independence of physicians and pathologists. Model 4 utilizes a comprehensive single bioresource bank; although in this case, the pathologists gain control of the samples, which may make it difficult to implement. Model 5, which employs a bioresource utilization steering committee (BUSC), is viable to implement and still maintains the advantages of Model 4. To comply with the upcoming law, we suggest that physicians and pathologists in an institution should collaborate to choose one of the improved models of tissue management system that best fits for their situation.

AB - Efficient management of human tissue samples is a critical issue; the supply of samples is unable to satisfy the current demands for research. Lack of informed consent is also an ethical problem. One of the goals of the 2012 revision of Korea's Bioethics and Safety Act was to implement regulations that govern the management of human tissue samples. To remain competitive, medical institutions must prepare for these future changes. In this report, we review two tissue management models that are currently in use; model 1 is the most common system utilized by hospitals in Korea and model 2 is implemented by some of the larger institutions. We also propose three alternative models that offer advantages over the systems currently in use. Model 3 is a multi-bank model that protects the independence of physicians and pathologists. Model 4 utilizes a comprehensive single bioresource bank; although in this case, the pathologists gain control of the samples, which may make it difficult to implement. Model 5, which employs a bioresource utilization steering committee (BUSC), is viable to implement and still maintains the advantages of Model 4. To comply with the upcoming law, we suggest that physicians and pathologists in an institution should collaborate to choose one of the improved models of tissue management system that best fits for their situation.

KW - Bioethics and safety act

KW - Bioresource bank

KW - Ethics committees

KW - Human tissue management model

KW - Research

UR - http://www.scopus.com/inward/record.url?scp=84880019829&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84880019829&partnerID=8YFLogxK

U2 - 10.3346/ jkms.2013.28.6.803

DO - 10.3346/ jkms.2013.28.6.803

M3 - Article

VL - 28

SP - 803

EP - 807

JO - Journal of Korean Medical Science

JF - Journal of Korean Medical Science

SN - 1011-8934

IS - 6

ER -