Analyzing coupled brain sources: Distinguishing true from spurious interaction

Guido Nolte, Andreas Ziehe, Frank Meinecke, Klaus Muller

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

When trying to understand the brain, it is of fundamental importance to analyse (e.g. from EEG/MEG measurements) what parts of the cortex interact with each other in order to infer more accurate models of brain activity. Common techniques like Blind Source Separation (BSS) can estimate brain sources and single out artifacts by using the underlying assumption of source signal independence. However, physiologically interesting brain sources typically interact, so BSS will-by construction - fail to characterize them properly. Noting that there are truly interacting sources and signals that only seemingly interact due to effects of volume conduction, this work aims to contribute by distinguishing these effects. For this a new BSS technique is proposed that uses anti-symmetrized cross-correlation matrices and subsequent diagonalization. The resulting decomposition consists of the truly interacting brain sources and suppresses any spurious interaction stemming from volume conduction. Our new concept of interacting source analysis (ISA) is successfully demonstrated on MEG data.

Original languageEnglish
Title of host publicationAdvances in Neural Information Processing Systems
Pages1027-1034
Number of pages8
Publication statusPublished - 2005 Dec 1
Externally publishedYes
Event2005 Annual Conference on Neural Information Processing Systems, NIPS 2005 - Vancouver, BC, Canada
Duration: 2005 Dec 52005 Dec 8

Other

Other2005 Annual Conference on Neural Information Processing Systems, NIPS 2005
CountryCanada
CityVancouver, BC
Period05/12/505/12/8

Fingerprint

Brain
Blind source separation
Electroencephalography
Decomposition

ASJC Scopus subject areas

  • Computer Networks and Communications
  • Information Systems
  • Signal Processing

Cite this

Nolte, G., Ziehe, A., Meinecke, F., & Muller, K. (2005). Analyzing coupled brain sources: Distinguishing true from spurious interaction. In Advances in Neural Information Processing Systems (pp. 1027-1034)

Analyzing coupled brain sources : Distinguishing true from spurious interaction. / Nolte, Guido; Ziehe, Andreas; Meinecke, Frank; Muller, Klaus.

Advances in Neural Information Processing Systems. 2005. p. 1027-1034.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nolte, G, Ziehe, A, Meinecke, F & Muller, K 2005, Analyzing coupled brain sources: Distinguishing true from spurious interaction. in Advances in Neural Information Processing Systems. pp. 1027-1034, 2005 Annual Conference on Neural Information Processing Systems, NIPS 2005, Vancouver, BC, Canada, 05/12/5.
Nolte G, Ziehe A, Meinecke F, Muller K. Analyzing coupled brain sources: Distinguishing true from spurious interaction. In Advances in Neural Information Processing Systems. 2005. p. 1027-1034
Nolte, Guido ; Ziehe, Andreas ; Meinecke, Frank ; Muller, Klaus. / Analyzing coupled brain sources : Distinguishing true from spurious interaction. Advances in Neural Information Processing Systems. 2005. pp. 1027-1034
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