Annulus fibrosus cells interact with neuron-like cells to modulate production of growth factors and cytokines in symptomatic disc degeneration

Medicine & Life Sciences

• Annulus Fibrosus 100%
• Intervertebral Disc Degeneration 87%
• Intercellular Signaling Peptides and Proteins 56%
• Cytokines 43%
• Neurons 43%
• Interleukin-1 21%
• Interleukin-8 15%
• Vascular Endothelial Growth Factor A 13%
• Tretinoin 11%
• Insulin-Like Growth Factor I 10%
• Coculture Techniques 10%
• Interleukin-6 8%
• Wounds and Injuries 7%
• Intractable Pain 6%
• Nerve Endings 6%
• Neuronal Outgrowth 6%
• Spinal Ganglia 5%
• Nerve Growth Factor 5%
• Conditioned Culture Medium 5%
• Neuroblastoma 5%
• Tears 5%
• Chronic Pain 4%
• Cultured Cells 4%
• Enzyme-Linked Immunosorbent Assay 3%
• Down-Regulation 3%
• Health Care Outcome Assessment 3%
• Cell Line 3%
• Pain 3%
• In Vitro Techniques 2%