Anti-cancer effects of disulfiram in head and neck squamous cell carcinoma via autophagic cell death

Agriculture & Biology

• disulfiram 99%
• antineoplastic activity 90%
• squamous cell carcinoma 90%
• autophagy 76%
• neck 62%
• reactive oxygen species 10%
• neoplasms 9%
• cell lines 6%
• alcohol abuse 4%
• carcinoma 4%
• drug therapy 4%
• cell death 4%
• animal models 3%
• copper 3%
• therapeutics 3%
• injection 2%
• cells 1%
• methodology 1%

Medicine & Life Sciences

• Autophagic Cell Death 93%
• Disulfiram 90%
• Squamous Cell Carcinoma of Head and Neck 72%
• Neoplasms 20%
• Reactive Oxygen Species 10%
• Heterografts 7%
• Cell Line 5%
• Copper 4%
• Alcoholism 3%
• Squamous Cell Carcinoma 3%
• Neck 3%
• Cell Death 3%
• Head 3%
• Animal Models 3%
• Down-Regulation 3%
• Injections 2%
• Survival 2%
• Growth 2%
• Therapeutics 1%

Chemical Compounds

• Disulfiram 100%
• Cell Death 68%
• Reactive Oxygen Metabolite 12%
• Apoptotic 4%
• Alcohol 2%