Anti-obese effects of chitosan and psyllium husk containing Vitamin C in Sprague-Dawley (SD) rats fed a high fat diet

Eun Young Jung, Yang Hee Hong, Un Jae Chang, Hyung Joo Suh

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1 Citation (Scopus)


We investigated whether Vitamin C would enhance the anti-obese effects of chitosan and psyllium husk. The study was carried out with male Sprague-Dawley (SD) rats for 6 wk using the following diet groups. Normal diet (control), high fat diet (F-control), 5% chitosan (chitosan-1), 5% chitosan containing 1% Vitamin C (chitosan-2), 10% psyllium husk (psyllium-1), and 10% psyllium husk containing 1% Vitamin C (psyllium-2). Chitosan-2 (1.5%) showed a significant (p<0.05) decrease in epididymal fat pad weight as compared to F-control (2.3%) and chitosan-1 (2.1%). The epididymal fat pad weight of psyllium-2 (1.9%) was significantly (p<0.05) lower than that of F-control (2.3%). In conclusion, additions of Vitamin C to chitosan and psyllium husk may be useful for reducing body fat.

Original languageEnglish
Pages (from-to)152-160
Number of pages9
JournalProgress in Nutrition
Issue number2
Publication statusPublished - 2016



  • Body fat
  • Body weight
  • Chitosan
  • Psyllium husk
  • Vitamin C

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics

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