Antihistamine pretreatment to reduce incidence of withdrawal movement after rocuronium injection

Ho Jun Lee; Sung Jin Han; Heezoo Kim; Il Ok Lee; Myoung Hoon Kong; Nan Suk Kim; Sang Ho Lim; Mi Kyoung Lee

doi:10.3346/jkms.2009.24.5.879

Antihistamine pretreatment to reduce incidence of withdrawal movement after rocuronium injection

Ho Jun Lee, Sung Jin Han, Heezoo Kim, Il Ok Lee, Myoung Hoon Kong, Nan Suk Kim, Sang Ho Lim, Mi Kyoung Lee

Department of Anesthesiology and Pain Medicine

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The purpose of this study was to determine the effectiveness of antihistamine therapy for withdrawal movements caused by rocuronium injection. One hundred seventy one ASA I-II adults undergoing elective surgery were randomly assigned to one of two groups. Patients in the control group (Group C) were premedicated with 2 mL normal saline, and those in the antihistamine group (Group A) were pre-medicated with 2 mL (45.5 mg) pheniramine maleate. After the administration of thiopental sodium 5 mg/kg, rocuronium 0.6 mg/kg was injected. Withdrawal movements were assessed using a four-grade scale. The administration of antihistamine reveals lower grade of withdrawal movement after rocuronium injection.

Original language	English
Pages (from-to)	879-882
Number of pages	4
Journal	Journal of Korean medical science
Volume	24
Issue number	5
DOIs	https://doi.org/10.3346/jkms.2009.24.5.879
Publication status	Published - 2009 Oct

Keywords

Antihistamine
Pain
Rocuronium

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.3346/jkms.2009.24.5.879

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title = "Antihistamine pretreatment to reduce incidence of withdrawal movement after rocuronium injection",

abstract = "The purpose of this study was to determine the effectiveness of antihistamine therapy for withdrawal movements caused by rocuronium injection. One hundred seventy one ASA I-II adults undergoing elective surgery were randomly assigned to one of two groups. Patients in the control group (Group C) were premedicated with 2 mL normal saline, and those in the antihistamine group (Group A) were pre-medicated with 2 mL (45.5 mg) pheniramine maleate. After the administration of thiopental sodium 5 mg/kg, rocuronium 0.6 mg/kg was injected. Withdrawal movements were assessed using a four-grade scale. The administration of antihistamine reveals lower grade of withdrawal movement after rocuronium injection.",

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AU - Lim, Sang Ho

AU - Lee, Mi Kyoung

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