Antimicrobial Activities of the Anti-acne Compounds from Natural Sources

Eun Sil Nam, Kim, Narae, Young Hee Lim, Sul Woong Park

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The in vitro antibacterial activities of anti-acne agents prepared from the extracts of natural sources were investigated against several bacteria including antibiotic-susceptible and -resistant Propionibacterium acnes. SD-1 and SD-2 were prepared with different formulations and they showed strong antibacterial activities. The anti-acne agents completely inhibited the growth of the tested strains at the concentration of 0.5%. There was no difference in antibacterial activity between antibiotic-susceptible and -resistant P. acnes. The inhibitory activities of two agents showed time-dependent manner. In S. aureus, time-kill curve demonstrated 2.8- and 3.4-log]o-unit killing after 8 h with SD-1 and SD-2, respectively. In P. acnes, time-killing curve demonstrated 5.1- and 6. l-logi0-unit killing after 24 h with SD-1 and SD-2, respectively. SD-2 showed stronger antimicrobial activity than SD-1. From these results, we expect that SD-1 and SD-2 have strong antibacterial activities and have advantages for treating acne.

Original languageEnglish
Pages (from-to)80-84
Number of pages5
JournalKorean Journal of Microbiology and Biotechnology
Volume37
Issue number1
Publication statusPublished - 2009 Mar 1

Fingerprint

Propionibacterium acnes
Acne Vulgaris
Anti-Bacterial Agents
Bacteria
Growth

Keywords

  • Anti-acne
  • Antimicrobial activity
  • Propionibacterium acnes

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Microbiology

Cite this

Antimicrobial Activities of the Anti-acne Compounds from Natural Sources. / Nam, Eun Sil; Kim; Narae, ; Lim, Young Hee; Park, Sul Woong.

In: Korean Journal of Microbiology and Biotechnology, Vol. 37, No. 1, 01.03.2009, p. 80-84.

Research output: Contribution to journalArticle

@article{d9c0c1c68c534e9fbab58b224ac259a2,
title = "Antimicrobial Activities of the Anti-acne Compounds from Natural Sources",
abstract = "The in vitro antibacterial activities of anti-acne agents prepared from the extracts of natural sources were investigated against several bacteria including antibiotic-susceptible and -resistant Propionibacterium acnes. SD-1 and SD-2 were prepared with different formulations and they showed strong antibacterial activities. The anti-acne agents completely inhibited the growth of the tested strains at the concentration of 0.5{\%}. There was no difference in antibacterial activity between antibiotic-susceptible and -resistant P. acnes. The inhibitory activities of two agents showed time-dependent manner. In S. aureus, time-kill curve demonstrated 2.8- and 3.4-log]o-unit killing after 8 h with SD-1 and SD-2, respectively. In P. acnes, time-killing curve demonstrated 5.1- and 6. l-logi0-unit killing after 24 h with SD-1 and SD-2, respectively. SD-2 showed stronger antimicrobial activity than SD-1. From these results, we expect that SD-1 and SD-2 have strong antibacterial activities and have advantages for treating acne.",
keywords = "Anti-acne, Antimicrobial activity, Propionibacterium acnes",
author = "Nam, {Eun Sil} and Kim and Narae and Lim, {Young Hee} and Park, {Sul Woong}",
year = "2009",
month = "3",
day = "1",
language = "English",
volume = "37",
pages = "80--84",
journal = "Korean Journal of Microbiology and Biotechnology",
issn = "1598-642X",
publisher = "Korean Society for Microbiolog and Biotechnology",
number = "1",

}

TY - JOUR

T1 - Antimicrobial Activities of the Anti-acne Compounds from Natural Sources

AU - Nam, Eun Sil

AU - Kim,

AU - Narae,

AU - Lim, Young Hee

AU - Park, Sul Woong

PY - 2009/3/1

Y1 - 2009/3/1

N2 - The in vitro antibacterial activities of anti-acne agents prepared from the extracts of natural sources were investigated against several bacteria including antibiotic-susceptible and -resistant Propionibacterium acnes. SD-1 and SD-2 were prepared with different formulations and they showed strong antibacterial activities. The anti-acne agents completely inhibited the growth of the tested strains at the concentration of 0.5%. There was no difference in antibacterial activity between antibiotic-susceptible and -resistant P. acnes. The inhibitory activities of two agents showed time-dependent manner. In S. aureus, time-kill curve demonstrated 2.8- and 3.4-log]o-unit killing after 8 h with SD-1 and SD-2, respectively. In P. acnes, time-killing curve demonstrated 5.1- and 6. l-logi0-unit killing after 24 h with SD-1 and SD-2, respectively. SD-2 showed stronger antimicrobial activity than SD-1. From these results, we expect that SD-1 and SD-2 have strong antibacterial activities and have advantages for treating acne.

AB - The in vitro antibacterial activities of anti-acne agents prepared from the extracts of natural sources were investigated against several bacteria including antibiotic-susceptible and -resistant Propionibacterium acnes. SD-1 and SD-2 were prepared with different formulations and they showed strong antibacterial activities. The anti-acne agents completely inhibited the growth of the tested strains at the concentration of 0.5%. There was no difference in antibacterial activity between antibiotic-susceptible and -resistant P. acnes. The inhibitory activities of two agents showed time-dependent manner. In S. aureus, time-kill curve demonstrated 2.8- and 3.4-log]o-unit killing after 8 h with SD-1 and SD-2, respectively. In P. acnes, time-killing curve demonstrated 5.1- and 6. l-logi0-unit killing after 24 h with SD-1 and SD-2, respectively. SD-2 showed stronger antimicrobial activity than SD-1. From these results, we expect that SD-1 and SD-2 have strong antibacterial activities and have advantages for treating acne.

KW - Anti-acne

KW - Antimicrobial activity

KW - Propionibacterium acnes

UR - http://www.scopus.com/inward/record.url?scp=64949199275&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=64949199275&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:64949199275

VL - 37

SP - 80

EP - 84

JO - Korean Journal of Microbiology and Biotechnology

JF - Korean Journal of Microbiology and Biotechnology

SN - 1598-642X

IS - 1

ER -