Antimicrobial activity of native chitosan, degraded chitosan, and O-carboxymethylated chitosan

Kyung W. Kim; R. L. Thomas; Chan Lee; Hyun J. Park

doi:10.4315/0362-028X-66.8.1495

Antimicrobial activity of native chitosan, degraded chitosan, and O-carboxymethylated chitosan

Kyung W. Kim, R. L. Thomas, Chan Lee, Hyun J. Park

Department of Biotechnology

Research output: Contribution to journal › Article › peer-review

91 Citations (Scopus)

Abstract

The antimicrobial activity of native chitosan was compared to that of lipase-degraded chitosan. The effects of O-carboxymethylated (O-CM) substitution on native (molecular weight, 120; degree of deacetylation, 84.71%) and lipase-degraded chitosans were also investigated. The antimicrobial activity of native chitosan was more extensive than that of lipase-degraded chitosan; however, lipase-degraded chitosan was still highly effective and more water-soluble. O-CM chitosan derived from degraded chitosan was more effective than O-CM chitosan derived from native chitosan. O-CM substitution enhanced lipase-degraded chitosan's antimicrobial activity without reducing its solubility.

Original language	English
Pages (from-to)	1495-1498
Number of pages	4
Journal	Journal of Food Protection
Volume	66
Issue number	8
DOIs	https://doi.org/10.4315/0362-028X-66.8.1495
Publication status	Published - 2003 Aug 1

ASJC Scopus subject areas

Food Science
Microbiology

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10.4315/0362-028X-66.8.1495

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AB - The antimicrobial activity of native chitosan was compared to that of lipase-degraded chitosan. The effects of O-carboxymethylated (O-CM) substitution on native (molecular weight, 120; degree of deacetylation, 84.71%) and lipase-degraded chitosans were also investigated. The antimicrobial activity of native chitosan was more extensive than that of lipase-degraded chitosan; however, lipase-degraded chitosan was still highly effective and more water-soluble. O-CM chitosan derived from degraded chitosan was more effective than O-CM chitosan derived from native chitosan. O-CM substitution enhanced lipase-degraded chitosan's antimicrobial activity without reducing its solubility.

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Antimicrobial activity of native chitosan, degraded chitosan, and O-carboxymethylated chitosan

Abstract

ASJC Scopus subject areas

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