TY - JOUR
T1 - Antimicrobial properties of chitosan and mode of action
T2 - A state of the art review
AU - Kong, Ming
AU - Chen, Xi Guang
AU - Xing, Ke
AU - Park, Hyun Jin
N1 - Funding Information:
This work was supported by grants from NSFC ( 30770582 ), ISTCP ( 2006DFA33150 ) and the Shandong Science Foundation ( Y2006C110 ), P. R. China.
PY - 2010/11/15
Y1 - 2010/11/15
N2 - Owing to its high biodegradability, and nontoxicity and antimicrobial properties, chitosan is widely-used as an antimicrobial agent either alone or blended with other natural polymers. To broaden chitosan's antimicrobial applicability, comprehensive knowledge of its activity is necessary. The paper reviews the current trend of investigation on antimicrobial activities of chitosan and its mode of action. Chitosan-mediated inhibition is affected by several factors can be classified into four types as intrinsic, environmental, microorganism and physical state, according to their respective roles. In this review, different physical states are comparatively discussed. Mode of antimicrobial action is discussed in parts of the active compound (chitosan) and the target (microorganisms) collectively and independently in same complex. Finally, the general antimicrobial applications of chitosan and perspectives about future studies in this field are considered.
AB - Owing to its high biodegradability, and nontoxicity and antimicrobial properties, chitosan is widely-used as an antimicrobial agent either alone or blended with other natural polymers. To broaden chitosan's antimicrobial applicability, comprehensive knowledge of its activity is necessary. The paper reviews the current trend of investigation on antimicrobial activities of chitosan and its mode of action. Chitosan-mediated inhibition is affected by several factors can be classified into four types as intrinsic, environmental, microorganism and physical state, according to their respective roles. In this review, different physical states are comparatively discussed. Mode of antimicrobial action is discussed in parts of the active compound (chitosan) and the target (microorganisms) collectively and independently in same complex. Finally, the general antimicrobial applications of chitosan and perspectives about future studies in this field are considered.
KW - Antimicrobial activity
KW - Application
KW - Chitosan
KW - Mechanism
UR - http://www.scopus.com/inward/record.url?scp=78149470032&partnerID=8YFLogxK
U2 - 10.1016/j.ijfoodmicro.2010.09.012
DO - 10.1016/j.ijfoodmicro.2010.09.012
M3 - Review article
C2 - 20951455
AN - SCOPUS:78149470032
SN - 0168-1605
VL - 144
SP - 51
EP - 63
JO - International Journal of Food Microbiology
JF - International Journal of Food Microbiology
IS - 1
ER -