Abstract
Background and objectives: This study was designed to investigate whether single epidural droperidol or continuous epidural droperidol inhibit pruritus and postoperative nausea and vomiting induced by postoperative continuous epidural fentanyl administration, and to identify the optimal method of administering epidural droperidol. Methods: 120 ASA I-II patients undergoing subtotal gastrectomy with general anaesthesia combined with epidural anaesthesia were randomly allocated into three groups: control (no droperidol), single injection (droperidol 2.5 mg) and continuous group (droperidol 2.5 mg 2 day -1). Postoperatively the frequency and severity of pruritus and postoperative nausea and vomiting in all groups were compared during 48 h. Results: The frequency and severity of pruritus was significantly lower in both single injection and continuous groups than control group after epidural fentanyl administration (P < 0.05). The frequency and severity of postoperative nausea and vomiting was significantly lower in single injection group than control group after epidural fentanyl administration (P < 0.05). Conclusion: Epidural continuous droperidol is effective for reducing pruritus, and single epidural droperidol injection is effective for reducing pruritus and postoperative nausea and vomiting induced by post-operative continuous epidural fentanyl analgesia.
| Original language | English |
|---|---|
| Pages (from-to) | 213-218 |
| Number of pages | 6 |
| Journal | European Journal of Anaesthesiology |
| Volume | 23 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2006 Mar 1 |
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Keywords
- Adverse effects
- ANaesthesia
- Droperidol
- Extradural
- Fentanyl
- Postoperative nausea and vomiting
- Pruritus
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
Cite this
Antipruritic and antiemetic effect of epidural droperidol : Comparative study between single and continuous epidural injection. / Lee, I. H.; Lee, Il Ok.
In: European Journal of Anaesthesiology, Vol. 23, No. 3, 01.03.2006, p. 213-218.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Antipruritic and antiemetic effect of epidural droperidol
T2 - Comparative study between single and continuous epidural injection
AU - Lee, I. H.
AU - Lee, Il Ok
PY - 2006/3/1
Y1 - 2006/3/1
N2 - Background and objectives: This study was designed to investigate whether single epidural droperidol or continuous epidural droperidol inhibit pruritus and postoperative nausea and vomiting induced by postoperative continuous epidural fentanyl administration, and to identify the optimal method of administering epidural droperidol. Methods: 120 ASA I-II patients undergoing subtotal gastrectomy with general anaesthesia combined with epidural anaesthesia were randomly allocated into three groups: control (no droperidol), single injection (droperidol 2.5 mg) and continuous group (droperidol 2.5 mg 2 day -1). Postoperatively the frequency and severity of pruritus and postoperative nausea and vomiting in all groups were compared during 48 h. Results: The frequency and severity of pruritus was significantly lower in both single injection and continuous groups than control group after epidural fentanyl administration (P < 0.05). The frequency and severity of postoperative nausea and vomiting was significantly lower in single injection group than control group after epidural fentanyl administration (P < 0.05). Conclusion: Epidural continuous droperidol is effective for reducing pruritus, and single epidural droperidol injection is effective for reducing pruritus and postoperative nausea and vomiting induced by post-operative continuous epidural fentanyl analgesia.
AB - Background and objectives: This study was designed to investigate whether single epidural droperidol or continuous epidural droperidol inhibit pruritus and postoperative nausea and vomiting induced by postoperative continuous epidural fentanyl administration, and to identify the optimal method of administering epidural droperidol. Methods: 120 ASA I-II patients undergoing subtotal gastrectomy with general anaesthesia combined with epidural anaesthesia were randomly allocated into three groups: control (no droperidol), single injection (droperidol 2.5 mg) and continuous group (droperidol 2.5 mg 2 day -1). Postoperatively the frequency and severity of pruritus and postoperative nausea and vomiting in all groups were compared during 48 h. Results: The frequency and severity of pruritus was significantly lower in both single injection and continuous groups than control group after epidural fentanyl administration (P < 0.05). The frequency and severity of postoperative nausea and vomiting was significantly lower in single injection group than control group after epidural fentanyl administration (P < 0.05). Conclusion: Epidural continuous droperidol is effective for reducing pruritus, and single epidural droperidol injection is effective for reducing pruritus and postoperative nausea and vomiting induced by post-operative continuous epidural fentanyl analgesia.
KW - Adverse effects
KW - ANaesthesia
KW - Droperidol
KW - Extradural
KW - Fentanyl
KW - Postoperative nausea and vomiting
KW - Pruritus
UR - http://www.scopus.com/inward/record.url?scp=33344472684&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33344472684&partnerID=8YFLogxK
U2 - 10.1017/S0265021505002218
DO - 10.1017/S0265021505002218
M3 - Article
C2 - 16430793
AN - SCOPUS:33344472684
VL - 23
SP - 213
EP - 218
JO - European Journal of Anaesthesiology
JF - European Journal of Anaesthesiology
SN - 0265-0215
IS - 3
ER -