APOE ε2/ε4 polymorphism and cerebral microbleeds on gradient-echo MRI

M. Kim, H. J. Bae, J. Lee, L. Kang, S. Lee, S. Kim, J. E. Lee, K. M. Lee, B. W. Yoon, O. Kwon, J. S. Koo, B. K. Kim

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Abstract

The association of APOE genotypes with cerebral microbleeds (CMBs) was examined on the basis of the location of CMBs in 414 patients who were admitted primarily because of stroke. With respect to possession of the ε2 or ε4 allele, the adjusted odds ratio was 1.94 (1.05 to 3.58) for lobar CMBs but 1.21 (0.69 to 2.11) for nonlobar CMBs. This suggests that the pathogenesis of CMBs may differ depending on their location.

Original languageEnglish
Pages (from-to)1474-1475
Number of pages2
JournalNeurology
Volume65
Issue number9
DOIs
Publication statusPublished - 2005 Nov 8

ASJC Scopus subject areas

  • Clinical Neurology

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    Kim, M., Bae, H. J., Lee, J., Kang, L., Lee, S., Kim, S., Lee, J. E., Lee, K. M., Yoon, B. W., Kwon, O., Koo, J. S., & Kim, B. K. (2005). APOE ε2/ε4 polymorphism and cerebral microbleeds on gradient-echo MRI. Neurology, 65(9), 1474-1475. https://doi.org/10.1212/01.wnl.0000183311.48144.7f