Apparent low-field microwave absorption in Escherichia coli endonuclease III: A possible way for increased DNA damage by the microwave effect

Sang Hwa Kim, Hag Dong Kim, Bu Hyun Youn, Chang Hoon Lee, Joon Kim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We observe an anomalous low-field microwave absorption for Escherichia coli endonuclease III in the process of measuring the electron magnetic resonance. To understand this, we firstly paid attention to a three-dimensional structure of the [4Fe-4S] cubane cluster existing in endonuclease III and then built fluctuating electric dipoles driven by both mixed-valence characteristics of a [4Fe-4S] cluster and its double exchange mechanism between Fe2+ and Fe3+. By using this model, we were able to explain the microwave absorption in terms of electric dipole transitions between excited states of the [4Fe-4S] cluster. Finally, a possible effect of this microwave absorption on a repair rate of the damaged-DNA is discussed.

Original languageEnglish
Pages (from-to)1065-1069
Number of pages5
JournalJournal of the Korean Physical Society
Volume52
Issue number4
DOIs
Publication statusPublished - 2008 Apr

Keywords

  • DNA damage
  • Microwave absorption
  • [4Fe-4S] cluster

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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