Application and validation of registration framework for real-time atlas guided biopsy

R. Narayanan, D. Shen, C. Davatzikos, D. E. Crawford, A. Barqawi, P. N. Werahera, D. Kumar, J. S. Suri

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

It is widely established that prostate cancer is a multifocal disease and cancerous lesions are not uniformly distributed within the gland. Current imaging methods cannot detect prostate cancer with sufficient sensitivity and specificity, especially localized cancers. A cancer atlas was previously demonstrated. However the atlas must be registered with a patient's ultrasound image in a clinical procedure. Here we present the fast registration of this atlas in a clinical setting so as to map cancer likelihoods in addition to optimized biopsy locations from the atlas space to the subject to maximize cancer detection accuracy. The registration was validated on 158 subjects with cancers annotated and the detection rate was found to be 84.81% and 89.87% for optimized 7 and 12 core biopsy schemes respectively. It took less than 8 seconds for the entire registration procedure.

Original languageEnglish
Title of host publication2008 5th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, Proceedings, ISBI
Pages1175-1178
Number of pages4
DOIs
Publication statusPublished - 2008
Externally publishedYes
Event2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI - Paris, France
Duration: 2008 May 142008 May 17

Publication series

Name2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI

Other

Other2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI
CountryFrance
CityParis
Period08/5/1408/5/17

Keywords

  • Atlas
  • Biopsy
  • Cancer
  • Prostate
  • Registration

ASJC Scopus subject areas

  • Biomedical Engineering

Fingerprint Dive into the research topics of 'Application and validation of registration framework for real-time atlas guided biopsy'. Together they form a unique fingerprint.

Cite this