TY - JOUR
T1 - Application of quorum sensing inhibitors for improving anti-biofouling of polyamide reverse osmosis membranes
T2 - Direct injection versus surface modification
AU - Kim, Jaehyeok
AU - Shin, Min Gyu
AU - Song, Won Jung
AU - Park, Sang Hee
AU - Ryu, Junhee
AU - Jung, Jaehyun
AU - Choi, Su Young
AU - Yu, Youngjae
AU - Kweon, Jihyang
AU - Lee, Jung Hyun
N1 - Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) Grant funded by the Korean Government ( Ministry of Science, ICT and Future Planning ) (No. 2018R1A2B2005745 ) and the Korea Institute of Energy Technology Evaluation and Planning (KETEP) and the Ministry of Trade, Industry and Energy (MOTIE) (No. 20194010201900 ).
Publisher Copyright:
© 2020 Elsevier B.V.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2021/1/15
Y1 - 2021/1/15
N2 - Quorum sensing inhibitors (QSIs) have shown promising results in reducing biofouling in various membrane systems. Vanillin was shown to inhibit QS of gram-negative bacteria during water treatment. Here, four vanillin-analogues with various chemical structures were used to understand the QS mechanisms in biofilm reduction and to compare direct dosing and surface modification of the inhibitors. Biofilm reduction, evaluated based on the content of extracellular polymeric substances (EPS), was the greatest with vanillin (49%) and occurred to some extent with 4-hydroxybenzaldehyde (21%) and m-anisaldehyde (13%), when direct dosing was applied. Experiments using vanillin-analogues revealed crucial roles of the chemical structure and functional groups on the inhibition of biofilm formation. The aldehyde and hydroxyl groups in both vanillin and 4-hydroxybenzaldehyde might be essential for QS inhibition. Further, surface modification with interfacial polymerization and immobilization of QSIs was conducted to evaluate their anti-biofouling capabilities. Surface modification was markedly effective in reducing biofilm formation; the EPS content of biofilms formed on vanillin-incorporated membranes was reduced by 64%. Additionally, the modified membranes showed a water flux comparable to that of pristine membranes, showing little possibility to block membrane pores during modification procedures. These findings will aid the development of QSI-based techniques for biofouling mitigation.
AB - Quorum sensing inhibitors (QSIs) have shown promising results in reducing biofouling in various membrane systems. Vanillin was shown to inhibit QS of gram-negative bacteria during water treatment. Here, four vanillin-analogues with various chemical structures were used to understand the QS mechanisms in biofilm reduction and to compare direct dosing and surface modification of the inhibitors. Biofilm reduction, evaluated based on the content of extracellular polymeric substances (EPS), was the greatest with vanillin (49%) and occurred to some extent with 4-hydroxybenzaldehyde (21%) and m-anisaldehyde (13%), when direct dosing was applied. Experiments using vanillin-analogues revealed crucial roles of the chemical structure and functional groups on the inhibition of biofilm formation. The aldehyde and hydroxyl groups in both vanillin and 4-hydroxybenzaldehyde might be essential for QS inhibition. Further, surface modification with interfacial polymerization and immobilization of QSIs was conducted to evaluate their anti-biofouling capabilities. Surface modification was markedly effective in reducing biofilm formation; the EPS content of biofilms formed on vanillin-incorporated membranes was reduced by 64%. Additionally, the modified membranes showed a water flux comparable to that of pristine membranes, showing little possibility to block membrane pores during modification procedures. These findings will aid the development of QSI-based techniques for biofouling mitigation.
KW - Biofouling reduction
KW - Quorum sensing inhibition
KW - Surface modification
KW - Vanillin
KW - Vanillin analogue
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U2 - 10.1016/j.seppur.2020.117736
DO - 10.1016/j.seppur.2020.117736
M3 - Article
AN - SCOPUS:85091572789
VL - 255
JO - Separation and Purification Technology
JF - Separation and Purification Technology
SN - 1383-5866
M1 - 117736
ER -