Aptamer-based sandwich-type biosensors

Ho Bin Seo, Man Bock Gu

Research output: Contribution to journalReview article

28 Citations (Scopus)

Abstract

Sandwich-type biosensor platforms have drawn lots of attentions due to its superior features, compared to other platforms, in terms of its stable and reproducible responses and easy enhancement in the detection sensitivity. The sandwich-type assays can be developed by utilizing a pair of receptors, which bind to the different sites of the same target. In this mini-review paper, the sandwich-type biosensors using either pairs of aptamers or aptamer-antibody pairs are reviewed in terms of its targets and platforms, the schematic designs, and their analytical performance.

Original languageEnglish
Article number11
JournalJournal of Biological Engineering
Volume11
Issue number1
DOIs
Publication statusPublished - 2017 Mar 13

Fingerprint

Biosensing Techniques
Biosensors
Schematic diagrams
Antibodies
Assays

Keywords

  • A pair of aptamer
  • Aptamer-antibody complex
  • Aptasensor
  • Sandwich-type aptasensor
  • Sandwich-type biosensors

ASJC Scopus subject areas

  • Environmental Engineering
  • Biomedical Engineering
  • Molecular Biology
  • Cell Biology

Cite this

Aptamer-based sandwich-type biosensors. / Seo, Ho Bin; Gu, Man Bock.

In: Journal of Biological Engineering, Vol. 11, No. 1, 11, 13.03.2017.

Research output: Contribution to journalReview article

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