Abstract
This paper describes a miniaturized oxygen sensor array integrated with heaters and temperature sensors and a LabVIEW-based measurement system which exactly can measure a cellular respiration level in a solution containing cells simultaneously. The designed oxygen sensor consists of Clark-type sensors, heaters, and temperature sensors of 2 x 3 array type on the substrate. 18μm PDMS was used for a permeable membrane of Clark-type sensor. The 90% response time was about 10 sec from full-oxygen (air-saturated) state to zero-oxygen (0.1M Na2SO3) state. The fabricated sensor showed good reproducibility for 1 hour with 3.15nA standard deviation of 108.2nA mean in the full-oxygen state and 0.14nA standard deviation of 1.33nA mean in the zero-oxygen state. Also, the fabricated sensor showed a good linearity with a correlation coefficient of 0.997. The LabVIEW-based measurement system composed to voltage supply module, amplifier module, DMM module, and temperature sensing module. In order to measure the cellular respiration level, the measurement program using LabVIEW was made. The ratio of uncoupled cellular oxygen consumption rate per coupled cellular oxygen consumption rate obtained by the fabricated sensors showed 1.96 which is almost the same as the value obtained from a commercial Oxygen-2K.
| Original language | English |
|---|---|
| Title of host publication | TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems |
| Pages | 1015-1018 |
| Number of pages | 4 |
| DOIs | |
| Publication status | Published - 2009 Dec 11 |
| Event | TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems - Denver, CO, United States Duration: 2009 Jun 21 → 2009 Jun 25 |
Other
| Other | TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems |
|---|---|
| Country | United States |
| City | Denver, CO |
| Period | 09/6/21 → 09/6/25 |
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Keywords
- Cellular respiration
- LabVIEW
- Oxygen sensor
- PDMS
ASJC Scopus subject areas
- Hardware and Architecture
- Electrical and Electronic Engineering
Cite this
Array type dissolved oxygen sensor and measurement system for simultaneous measurement of cellular respiration level. / Park, Jung ho; Chang, J. H.; Ahn, S.; Pak, Y. K.; Han, S.; Pak, James Jungho.
TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems. 2009. p. 1015-1018 5285960.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Array type dissolved oxygen sensor and measurement system for simultaneous measurement of cellular respiration level
AU - Park, Jung ho
AU - Chang, J. H.
AU - Ahn, S.
AU - Pak, Y. K.
AU - Han, S.
AU - Pak, James Jungho
PY - 2009/12/11
Y1 - 2009/12/11
N2 - This paper describes a miniaturized oxygen sensor array integrated with heaters and temperature sensors and a LabVIEW-based measurement system which exactly can measure a cellular respiration level in a solution containing cells simultaneously. The designed oxygen sensor consists of Clark-type sensors, heaters, and temperature sensors of 2 x 3 array type on the substrate. 18μm PDMS was used for a permeable membrane of Clark-type sensor. The 90% response time was about 10 sec from full-oxygen (air-saturated) state to zero-oxygen (0.1M Na2SO3) state. The fabricated sensor showed good reproducibility for 1 hour with 3.15nA standard deviation of 108.2nA mean in the full-oxygen state and 0.14nA standard deviation of 1.33nA mean in the zero-oxygen state. Also, the fabricated sensor showed a good linearity with a correlation coefficient of 0.997. The LabVIEW-based measurement system composed to voltage supply module, amplifier module, DMM module, and temperature sensing module. In order to measure the cellular respiration level, the measurement program using LabVIEW was made. The ratio of uncoupled cellular oxygen consumption rate per coupled cellular oxygen consumption rate obtained by the fabricated sensors showed 1.96 which is almost the same as the value obtained from a commercial Oxygen-2K.
AB - This paper describes a miniaturized oxygen sensor array integrated with heaters and temperature sensors and a LabVIEW-based measurement system which exactly can measure a cellular respiration level in a solution containing cells simultaneously. The designed oxygen sensor consists of Clark-type sensors, heaters, and temperature sensors of 2 x 3 array type on the substrate. 18μm PDMS was used for a permeable membrane of Clark-type sensor. The 90% response time was about 10 sec from full-oxygen (air-saturated) state to zero-oxygen (0.1M Na2SO3) state. The fabricated sensor showed good reproducibility for 1 hour with 3.15nA standard deviation of 108.2nA mean in the full-oxygen state and 0.14nA standard deviation of 1.33nA mean in the zero-oxygen state. Also, the fabricated sensor showed a good linearity with a correlation coefficient of 0.997. The LabVIEW-based measurement system composed to voltage supply module, amplifier module, DMM module, and temperature sensing module. In order to measure the cellular respiration level, the measurement program using LabVIEW was made. The ratio of uncoupled cellular oxygen consumption rate per coupled cellular oxygen consumption rate obtained by the fabricated sensors showed 1.96 which is almost the same as the value obtained from a commercial Oxygen-2K.
KW - Cellular respiration
KW - LabVIEW
KW - Oxygen sensor
KW - PDMS
UR - http://www.scopus.com/inward/record.url?scp=71449087550&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=71449087550&partnerID=8YFLogxK
U2 - 10.1109/SENSOR.2009.5285960
DO - 10.1109/SENSOR.2009.5285960
M3 - Conference contribution
AN - SCOPUS:71449087550
SN - 9781424441938
SP - 1015
EP - 1018
BT - TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
ER -